Health hazard · Acute toxicity - inhalation
H330 — Fatal if inhaled
Health hazard statements describe what the substance does to a person exposed to it. 189 substances with a harmonised EU classification carry this code.
01 · Wording
What H330 says
Fatal if inhaled.
CLP Annex III · Health hazards
Acute toxicity - inhalation GHS chapter 3.1
Category 2, 1 · pictogram GHS06 (skull and crossbones) · signal word Danger
Unchanged since 2009.
Present in every UN GHS edition from Rev.3 (2009) to Rev.11 (2025), with the same wording throughout.
Nine editions of the UN model text, 86 hazard statements, 19 of which ever moved. Read the full story in what changed in UN GHS Rev.11.
02 · Legal status
Where H330 is current
GHS is a United Nations model text, revised every two years, and each jurisdiction adopts a revision on its own timetable. A code can be legally current in one system and deleted in another — that is normal, not an error.
| Jurisdiction | Basis | Status of H330 |
|---|---|---|
| EU CLP | Regulation (EC) 1272/2008 CLP Annex IV, Part 2 (consolidated) | Current |
| US OSHA HazCom | 29 CFR 1910.1200 Appendix C UN GHS Rev.7 (final rule of 20 May 2024) | Current |
| US HazCom 2012 | legacy · GHS Rev.3 UN GHS Rev.3, Annex 3 | Current |
| UN GHS | Rev.11 (2025) UN GHS Rev.11, Annex 3 | Current |
Currently in force under: EU CLP, US OSHA HazCom, US HazCom 2012, UN GHS. Sources: EU CLP · US OSHA HazCom · US HazCom 2012 · UN GHS
03 · On a label
H330 also appears combined
CLP Annex III defines combined hazard statements as single label elements. H330 is a component of 3 of them — this is how you will actually see it printed. The combinations have no pages of their own: a plus sign in a URL has to be encoded and breaks in other people's links and in analytics.
| Code | Combined statement |
|---|---|
| H300+H330 | Fatal if swallowed or if inhaled. CLP verbatim: Fatal if swallowed or if inhaled |
| H310+H330 | Fatal in contact with skin or if inhaled. CLP verbatim: Fatal in contact with skin or if inhaled |
| H300+H310+H330 | Fatal if swallowed, in contact with skin or if inhaled. CLP verbatim: Fatal if swallowed, in contact with skin or if inhaled |
04 · Substances
Substances carrying H330
Every entry whose harmonised CLP Annex VI classification includes this hazard statement. Substances with a reference page here open on this site; the rest open on ghssymbols.com. Of these, 18 are group entries such as “salts of picric acid” or “beryllium compounds” — Annex VI gives them no CAS number, so they are listed by Index No and have no page of their own.
- (benzothiazol-2-ylthio)methyl thiocyanate; TCMTB CAS 21564-17-0
- (RS)-4-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole;; medetomidine CAS 86347-14-0
- 1,1,2,2-tetrabromoethane CAS 79-27-6
- 1,1,2,2-tetrachloroethane CAS 79-34-5
- 1,2-benzisothiazol-3(2H)-one; 1,2-benzisothiazolin-3-one CAS 2634-33-5
- 1,3,5-trinitrobenzene CAS 99-35-4
- 1,4-dichlorobut-2-ene CAS 764-41-0
- 2-(3-(prop-1-en-2-yl)phenyl)prop-2-yl isocyanate CAS 2094-99-7
- 2-chloro-1,3,5-trinitrobenzene CAS 88-88-0
- 2-chloroethanol; ethylene chlorohydrin CAS 107-07-3
- 2-hydroxy-2-methylpropionitrile; 2-cyanopropan-2-ol; acetone cyanohydrin CAS 75-86-5
- 2-methylaziridine; propyleneimine CAS 75-55-8
- 2-methylisothiazol-3(2H)-one CAS 2682-20-4
- 2-nitro-p-anisidine; 4-methoxy-2-nitroaniline CAS 96-96-8
- 2,2-dibromo-2-cyanoacetamide; [DBNPA] CAS 10222-01-2
- 2,2'-bioxirane; 1,2:3,4-diepoxybutane CAS 1464-53-5
- 2,4-dinitroaniline CAS 97-02-9
- 2,4,6-trichloro-1,3,5-triazine; cyanuric chloride CAS 108-77-0
- 2,5-bis-isocyanatomethyl-bicyclo[2.2.1]heptane Index No 615-029-00-X
- 3-propanolide; 1,3-propiolactone CAS 57-57-8
- 3,3'-iminodi(propylamine); dipropylenetriamine CAS 56-18-8
- 4-chlorophenylisocyanate CAS 104-12-1
- 4,4,5,5-tetrachloro-1,3-dioxolan-2-one CAS 22432-68-4
- 4,5-dichloro-2-octyl- 2H-isothiazol-3-one; [DCOIT] CAS 64359-81-5
- abamectin (combination of avermectin B1a and avermectin B1b) (ISO) [1]; avermectin B1a (purity ≥80 %) [2] CAS 71751-41-2[1]65195-5
- aconitine CAS 302-27-2
- acrolein; prop-2-enal; acrylaldehyde CAS 107-02-8
- aldicarb (ISO); 2-methyl-2-(methylthio)propanal-O-(N-methylcarbamoyl)oxime CAS 116-06-3
- allyl methacrylate; 2-methyl-2-propenoic acid 2-propenyl ester CAS 96-05-9
- aluminium phosphide CAS 20859-73-8
- ammonium dichromate CAS 7789-09-5
- ammonium salt of DNOC; ammonium 4,6-dinitro-o-tolyl oxide CAS 2980-64-5
- arsine CAS 7784-42-1
- atropine CAS 51-55-8
- azinphos-methyl (ISO); O,O-dimethyl-4-oxobenzotriazin-3-ylmethyl phosphorodithioate CAS 86-50-0
- azocyclotin (ISO); 1-(tricyclohexylstannyl)-1H-1,2,4-triazole CAS 41083-11-8
- beryllium CAS 7440-41-7
- beryllium compounds with the exception of aluminium beryllium silicates, and with those specified elsewhere in this Annex Index No 004-002-00-2
- beryllium oxide CAS 1304-56-9
- beta-cyfluthrin (ISO);; reaction mass of rel-(R)-cyano(4-fluoro-3-phenoxyphenyl)methyl(1S,3S)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate and rel-(R)-cyano(4-fluoro-3-phenoxyphenyl)methyl(1S,3R)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate CAS 1820573-27-0
- bis(2-chloroethyl) ether CAS 111-44-4
- bis(2,4,6-trinitrophenyl)amine; hexyl CAS 131-73-7
- bis(chloromethyl) ether; oxybis(chloromethane) CAS 542-88-1
- boron tribromide CAS 10294-33-4
- boron trichloride CAS 10294-34-5
- boron trifluoride CAS 7637-07-2
- brodifacoum (ISO); 4-hydroxy-3-(3-(4'-bromo-4-biphenylyl)-1,2,3,4-tetrahydro-1-naphthyl)coumarin CAS 56073-10-0
- bromadiolone (ISO); 3-[3-(4′-bromobiphenyl-4-yl)-3-hydroxy-1-phenylpropyl]-4-hydroxy-2H-chromen-2-one CAS 28772-56-7
- bromine CAS 7726-95-6
- bromoxynil (ISO); 3,5-dibromo-4-hydroxybenzonitrile; bromoxynil phenol CAS 1689-84-5
- brucine sulphate [1]; brucine nitrate [2]; Strychnidin-10-one, 2,3-dimethoxy-, mono[(R)-1-methylheptyl 1,2-benzenedicarboxylate] [3]; Strychnidin-10-one, 2,3-dimethoxy-, compd. with (S)mono(1-methylheptyl)-1,2-benzenedicarboxylate (1:1) [4] CAS 4845-99-2[1]5786-97-
- brucine; 2,3-dimethoxystrychnine CAS 357-57-3
- cadmium CAS 7440-43-9
- cadmium (non-pyrophoric) [1]; cadmium oxide (non-pyrophoric) [2] CAS 7440-43-9[1]1306-19-
- cadmium chloride CAS 10108-64-2
- cadmium cyanide CAS 542-83-6
- cadmium fluoride CAS 7790-79-6
- cadmium sulphate CAS 10124-36-4
- calcium phosphide; tricalcium diphosphide CAS 1305-99-3
- carbofuran (ISO); 2,3-dihydro-2,2-dimethylbenzofuran-7-yl N-methylcarbamate CAS 1563-66-2
- carbosulfan (ISO); 2,3-dihydro-2,2-dimethyl-7-benzofuryl [(dibutylamino)thio]methylcarbamate CAS 55285-14-8
- chlorine dioxide CAS 10049-04-4
- chloroacetaldehyde CAS 107-20-0
- chloronitroanilines with the exception of those specified elsewhere in this Annex Index No 610-006-00-0
- chlorophacinone (ISO); 2-[(4-chlorophenyl)(phenyl)acetyl]-1H-indene-1,3(2H)-dione CAS 3691-35-8
- chlorothalonil (ISO); tetrachloroisophthalonitrile CAS 1897-45-6
- chromium trioxide CAS 1333-82-0
- colecalciferol;; cholecalciferol;; Vitamin D3 CAS 67-97-0
- copper dihydroxide; copper(II) hydroxide CAS 20427-59-2
- coumatetralyl (ISO); 4-hydroxy-3-(1,2,3,4-tetrahydro-1-naphthyl)coumarin CAS 5836-29-3
- crotonaldehyde; 2-butenal [1]; (E)-2-butenal; (E)-crotonaldehyde [2] CAS 4170-30-3[1]123-73-9
- cyfluthrin (ISO); α-cyano-4-fluoro-3-phenoxybenzyl-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate CAS 68359-37-5
- di-n-butylamine CAS 111-92-2
- dibutyltin dichloride; (DBTC) CAS 683-18-1
- dibutyltin maleate CAS 78-04-6
- dichlorodioctylstannane CAS 3542-36-7
- dichlorvos (ISO); 2,2-dichlorovinyl dimethyl phosphate CAS 62-73-7
- difenacoum (ISO); 3-(3-biphenyl-4-yl-1,2,3,4-tetrahydro-1-naphthyl)-4-hydroxycoumarin CAS 56073-07-5
- difethialone (ISO);; 3-[3-(4′-bromobiphenyl-4-yl)-1,2,3,4-tetrahydronaphthalen-1-yl]-4-hydroxy-2H-1-benzothiopyran-2-one CAS 104653-34-1
- dimethyl sulphate CAS 77-78-1
- dimethylmercury [1]; diethylmercury [2] CAS 593-74-8[1]627-44-1[
- dimethylnitrosoamine; N-nitrosodimethylamine CAS 62-75-9
- dimethylsulfamoylchloride CAS 13360-57-1
- dimethyltin dichloride CAS 753-73-1
- dinitrobenzene [1]; 1,4-dinitrobenzene [2]; 1,3-dinitrobenzene [3]; 1,2-dinitrobenzene [4] CAS 25154-54-5[1]100-25-
- dioxathion (ISO); 1,4-dioxan-2,3-diyl-O,O,O',O'-tetraethyl di(phosphorodithioate) CAS 78-34-2
- dipicrylamine, ammonium salt CAS 2844-92-0
- diquat dibromide [1]; diquat dichloride [2]; 6,7-dihydrodipyrido[1,2-α:2',1'-c]pyrazinediylium dihydroxide [3] CAS 85-00-7[1]4032-26-2[
- divanadium pentaoxide; vanadium pentoxide CAS 1314-62-1
- DNOC (ISO); 4,6-dinitro-o-cresol CAS 534-52-1
- endosulfan (ISO); 1,2,3,4,7,7-hexachloro-8,9,10-trinorborn-2-en-5,6-ylenedimethylene sulfite; 1,4,5,6,7,7-hexachloro-8,9,10-trinorborn-5-en-2,3-ylenedimethylene sulfite CAS 115-29-7
- ergocalciferol (ISO); Vitamin D2 CAS 50-14-6
- ethidium bromide; 3,8-diamino-1-ethyl-6-phenylphenantridinium bromide CAS 1239-45-8
- ethoprophos (ISO); ethyl-S,S-dipropyl phosphorodithioate CAS 13194-48-4
- ethyl bromoacetate CAS 105-36-2
- ethyl chloroformate CAS 541-41-3
- ethylene dinitrate; ethylene glycol dinitrate CAS 628-96-6
- ethyleneimine; aziridine CAS 151-56-4
- fenamiphos (ISO); ethyl-4-methylthio-m-tolyl isopropyl phosphoramidate CAS 22224-92-6
- fenbutatin oxide (ISO); bis(tris(2-methyl-2-phenylpropyl)tin)oxide CAS 13356-08-6
- fenpropathrin (ISO); α-cyano-3-phenoxybenzyl 2,2,3,3-tetramethylcyclopropanecarboxylate CAS 39515-41-8
- fenpyroximate (ISO); tert-butyl 4-[({(E)-[(1,3-dimethyl-5-phenoxy-1H-pyrazol-4-yl)methylene]amino}oxy)methyl]benzoate CAS 134098-61-6
- fentin acetate (ISO); triphenyltin acetate CAS 900-95-8
- fentin hydroxide (ISO); triphenyltin hydroxide CAS 76-87-9
- flocoumafen (ISO); reaction mass of: cis-4-hydroxy-3-(1,2,3,4-tetrahydro-3-(4-(4-trifluoromethylbenzyloxy)phenyl)-1-naphthyl)coumarin and trans-4-hydroxy-3-(1,2,3,4-tetrahydro-3-(4-(4-trifluoromethylbenzyloxy)phenyl)-1-naphthyl)coumarin CAS 90035-08-8
- fluorine CAS 7782-41-4
- formaldehyde CAS 50-00-0
- formetanate (ISO); 3-[(EZ)-dimethylaminomethyleneamino]phenyl methylcarbamate CAS 22259-30-9
- formetanate hydrochloride; 3-(N,N-dimethylaminomethyleneamino)phenyl N-methylcarbamate CAS 23422-53-9
- furathiocarb (ISO); 2,3-dihydro-2,2-dimethyl-7-benzofuryl 2,4-dimethyl-6-oxa-5-oxo-3-thia-2,4-diazadecanoate CAS 65907-30-4
- glutaraldehyde CAS 111-30-8
- glycerol trinitrate; nitroglycerine CAS 55-63-0
- guazatine (ISO) CAS 108173-90-6
- hexachlorocyclopentadiene CAS 77-47-4
- hydrofluoric acid CAS 7664-39-3
- hydrogen cyanide; hydrocyanic acid CAS 74-90-8
- hydrogen sulphide, hydrogen sulfide CAS 7783-06-4
- hyoscine CAS 51-34-3
- hyoscyamine CAS 101-31-5
- inorganic compounds of mercury with the exception of mercuric sulphide and those specified elsewhere in this Annex Index No 080-002-00-6
- isazofos (ISO); O-(5-chloro-1-isopropyl-1,2,4-triazol-3-yl) O,O-diethyl phosphorothioate CAS 42509-80-8
- isodrin; (1α,4α,4aβ,5β,8β,8aβ)-1,2,3,4,10,10-hexachloro-1,4,4a,5,8,8a-hexahydro-1,4:5,8-dimethanonaphthalene CAS 465-73-6
- lambda-cyhalothrin (ISO); reaction mass of (S)-α-cyano-3-phenoxybenzyl(Z)-(1R)-cis-3-(2-chloro-3,3,3-trifluoropropenyl)-2,2-dimethylcyclopropanecarboxylate and (R)-α-cyano-3-phenoxybenzyl (Z)-(1S)-cis-3-(2-chloro-3,3,3-trifluoropropenyl)-2,2-dimethylcyclopropanecarboxylate (1:1) CAS 91465-08-6
- lead alkyls Index No 082-002-00-1
- magnesium phosphide; trimagnesium diphosphide CAS 12057-74-8
- mercury CAS 7439-97-6
- methamidophos (ISO); O,S-dimethyl phosphoramidothioate CAS 10265-92-6
- methyl chloroformate CAS 79-22-1
- methyl isocyanate CAS 624-83-9
- methylene dithiocyanate CAS 6317-18-6
- methylmercuric chloride CAS 115-09-3
- monocrotophos (ISO); dimethyl-1-methyl-2-(methylcarbamoyl)vinyl phosphate CAS 6923-22-4
- neodecanoyl chloride CAS 40292-82-8
- nicotine (ISO);; 3-[(2S)-1-methylpyrrolidin-2-yl]pyridine CAS 54-11-5
- nitric acid CAS 7697-37-2
- nitrogen dioxide [1]; dinitrogen tetraoxide [2] CAS 10102-44-0[1]10544-7
- octhilinone (ISO); 2-octyl-2H-isothiazol-3-one; [OIT] CAS 26530-20-1
- organic compounds of mercury with the exception of those specified elsewhere in this Annex Index No 080-004-00-7
- osmium tetraoxide; osmic acid CAS 20816-12-0
- oxamyl (ISO); N',N'-dimethylcarbamoyl(methylthio)methylenamine N-methylcarbamate CAS 23135-22-0
- oxydiethylene dinitrate; diethylene glycol dinitrate; digol dinitrate CAS 693-21-0
- p-anisidine; 4-methoxyaniline CAS 104-94-9
- paraquat dichloride; 1,1-dimethyl-4,4'-bipyridinium dichloride [1]; paraquat dimethylsulfate; 1,1-dimethyl-4,4'-bipyridinium dimethyl sulphate [2] CAS 1910-42-5[1]2074-50-
- parathion - methyl (ISO); O,O-dimethyl O-4-nitrophenyl phosphorothioate CAS 298-00-0
- parathion (ISO); O,O-diethyl O-4-nitrophenyl phosphorothioate CAS 56-38-2
- pentachlorophenol CAS 87-86-5
- peracetic acid . . . % CAS 79-21-0
- phosgene; carbonyl chloride CAS 75-44-5
- phosphine CAS 7803-51-2
- phosphorus pentachloride CAS 10026-13-8
- phosphorus trichloride CAS 7719-12-2
- phosphoryl trichloride CAS 10025-87-3
- physostigmine CAS 57-47-6
- pilocarpine CAS 92-13-7
- polyhexamethylene biguanide hydrochloride; PHMB [1]; PHMB [2] CAS 32289-58-0[1]27083-2
- potasan; O,O-diethyl O-(4-methylcoumarin-7-yl) phosphorothioate CAS 299-45-6
- potassium dichromate CAS 7778-50-9
- pyrazoxon; diethyl 3-methylpyrazol-5-yl phosphate CAS 108-34-9
- pyrithione zinc; (T-4)- bis[1-(hydroxy-.kappa.O)pyridine-2(1H)- thionato-.kappa.S]zinc CAS 13463-41-7
- reaction mass of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-2H-isothiazol-3-one (3:1) CAS 55965-84-9
- S-[2-(ethylsulphinyl)ethyl] O,O-dimethyl phosphorodithioate CAS 2703-37-9
- salts of aconitine Index No 614-009-00-8
- salts of atropine Index No 614-011-00-9
- salts of bromoxynil with the exception of those specified elsewhere in this Annex Index No 608-065-00-2
- salts of hyoscine Index No 614-015-00-0
- salts of hyoscyamine Index No 614-013-00-X
- salts of nicotine Index No 614-002-00-X
- salts of physostigmine Index No 614-021-00-3
- salts of pilocarpine Index No 614-017-00-1
- salts of strychnine Index No 614-004-00-0
- sodium chromate CAS 7775-11-3
- sodium dichromate CAS 10588-01-9
- sodium fluoroacetate CAS 62-74-8
- sodium pentachlorophenolate [1]; potassium pentachlorophenolate [2] CAS 131-52-2[1]7778-73-6
- tefluthrin (ISO);; 2,3,5,6-tetrafluoro-4-methylbenzyl (1RS,3RS)-3-[(Z)-2-chloro-3,3,3-trifluoroprop-1-enyl]-2,2-dimethylcyclopropanecarboxylate CAS 79538-32-2
- tert-butylarsine CAS 4262-43-5
- tetracarbonylnickel; nickel tetracarbonyl CAS 13463-39-3
- thallium CAS 7440-28-0
- thallium compounds, with the exception of those specified elsewhere in this Annex Index No 081-002-00-9
- thallium thiocyanate CAS 3535-84-0
- toluene diisocyanate CAS 91-08-7[1]584-84-9[2
- tolylfluanid (ISO); dichloro-N- [(dimethylamino)sulphonyl]fluoro-N-(p-tolyl)methanesulphenamide; [containing ≥ 0.1 % (w/w) of particles with an aerodynamic diameter of below 50 µm] CAS 731-27-1
- trichloronitromethane; chloropicrin CAS 76-06-2
- triethyltin compounds, with the exception of those specified elsewhere in this Annex Index No 050-006-00-2
- trimethyltin compounds, with the exception of those specified elsewhere in this Annex Index No 050-005-00-7
- uranium CAS 7440-61-1
- warfarin (ISO); 4-hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one [1]; (S)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone [2]; (R)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone [3] CAS 81-81-2[1]5543-57-7[
- white phosphorus CAS 12185-10-3
- ziram (ISO); zinc bis dimethyldithiocarbamate CAS 137-30-4
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The full list of H-codes with the jurisdiction switch lives on the hazard statements hub. For what to do about the hazard, see precautionary statements (P-codes).
Wording quoted from the regulation named above. Substance counts come from harmonised classifications in CLP Annex VI — the statements on a real product also depend on the supplier's own classification. Always check the supplier safety data sheet.