GHS Hazard Pictogram
GHS06
Skull and Crossbones
Acute toxicity (severe)
What does GHS06 mean?
The skull and crossbones pictogram indicates severe acute toxicity via oral (H300/H301), dermal (H310/H311), or inhalation (H330/H331) routes. Categories 1–3 represent the highest acute toxicity levels under GHS/CLP.
Associated H-statements (6)
Storage & handling requirements
Store in locked, well-ventilated area. Access restricted to trained and authorised personnel only. Secondary containment mandatory. Biological and air monitoring may be required. Emergency procedures and antidotes must be available and documented.
Regulatory context (CLP / OSHA / REACH)
CLP Acute Toxicity Cat. 1–3. Suppresses GHS07 on labels per CLP Article 26. OSHA 29 CFR 1910.1200 requires full hazcom programme. EU occupational exposure limits (OELs) under Directive 2017/164/EU may apply.
Transport marking: GHS vs ADR/DOT
ADR Class 6.1 — Toxic substances. White diamond with skull and crossbones. Packing group I (very toxic), II (toxic), or III (harmful). Closed cargo transport vehicles required for PG I liquids.
GHS06 — Skull and Crossbones
High-resolution SVG vector file. Free for use in safety documents, SDS, and label design.
Substances classified with GHS06
Showing 24 of 604 substances in our database with this pictogram. View all →
- 2,2,4-trimethylhexamethylene-1,6-di-isocyanate [1] 2,4,4-trimethylhexamethylene-1,6-di-isocyanate [2] CAS 16938-22-0[1]15646-9Danger Details →Label
- 4-chlorophenylisocyanate CAS 104-12-1Danger Details →Label
- pirimicarb (ISO); 2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl dimethylcarbamate CAS 23103-98-2Danger Details →Label
- bufencarb (ISO); reaction mass of 3-(1-methylbutyl)phenyl N-methylcarbamate and 3-(1-ethylpropyl)phenyl N-methylcarbamate CAS 8065-36-9Danger Details →Label
- 2-(3-(prop-1-en-2-yl)phenyl)prop-2-yl isocyanate CAS 2094-99-7Danger Details →Label
- O-ethylhydroxylamine CAS 624-86-2Danger Details →Label
- phosphamidon (ISO); 2-chloro-2-diethylcarbamoyl-1-methylvinyl dimethyl phosphate CAS 13171-21-6Danger Details →Label
- azinphos-methyl (ISO); O,O-dimethyl-4-oxobenzotriazin-3-ylmethyl phosphorodithioate CAS 86-50-0Danger Details →Label
- disulfoton (ISO); O,O-diethyl 2-ethylthioethyl phosphorodithioate CAS 298-04-4Danger Details →Label
- azinphos-ethyl (ISO); O,O-diethyl 4-oxobenzotriazin-3-ylmethyl phosphorodithioate CAS 2642-71-9Danger Details →Label
- 2,2-dichlorovinyl 2-ethylsulphinylethyl methyl phosphate CAS 7076-53-1Danger Details →Label
- demeton-S-methylsulphon (ISO); S-2-ethylsulphonylethyl dimethyl phosphorothioate CAS 17040-19-6Danger Details →Label
- oxydisulfoton (ISO); O, O-diethyl S-2-ethylsulphinylethyl phosphorodithioate CAS 2497-07-6Danger Details →Label
- demephion-O (ISO); O,O-dimethyl O-2-methylthioethyl phosphorothioate CAS 682-80-4Danger Details →Label
- isofenphos (ISO); O-ethyl O-2-isopropoxycarbonylphenyl-isopropylphosphoramidothioate CAS 25311-71-1Danger Details →Label
- triazophos (ISO); O,O-diethyl-O-1-phenyl-1H-1,2,4-triazol-3-yl phosphorothioate CAS 24017-47-8Danger Details →Label
- fosthiazate (ISO); (RS)-S-sec-butyl-O-ethyl-2-oxo-1,3-thiazolidin-3-ylphosphonothioate CAS 98886-44-3Danger Details →Label
- tert-butyl (triphenylphosphoranylidene) acetate CAS 35000-38-5Danger Details →Label
- chlorine dioxide CAS 10049-04-4Danger Details →Label
- divanadium pentaoxide; vanadium pentoxide CAS 1314-62-1Danger Details →Label
- nickel dichloride CAS 7718-54-9Danger Details →Label
- tert-butylarsine CAS 4262-43-5Danger Details →Label
- cadmium diformate; cadmiumformate CAS 4464-23-7Danger Details →Label
- mercury difulminate; mercuric fulminate; fulminate of mercury CAS 628-86-4Danger Details →Label
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