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GHS Hazard Pictogram

GHS08

Health Hazard

Serious long-term health hazards

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What does GHS08 mean?

The health hazard pictogram indicates serious chronic or irreversible health effects: carcinogenicity (H350/H351), mutagenicity (H340/H341), reproductive toxicity (H360/H361/H362), respiratory sensitisation (H334), and specific target organ toxicity (H370–H373).

Associated H-statements (12)

H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled.
H340 May cause genetic defects.
H341 Suspected of causing genetic defects.
H350 May cause cancer.
H351 Suspected of causing cancer.
H360 May damage fertility or the unborn child.
H361 Suspected of damaging fertility or the unborn child.
H362 May cause harm to breast-fed children.
H370 Causes damage to organs.
H371 May cause damage to organs.
H372 Causes damage to organs through prolonged or repeated exposure.
H373 May cause damage to organs through prolonged or repeated exposure.

Storage & handling requirements

Minimise exposure using engineering controls: local exhaust ventilation, closed systems, gloveboxes. Biological monitoring and medical surveillance may be legally required. Substitution should be considered for Cat. 1A/1B substances. Restrict access and maintain exposure records.

Regulatory context (CLP / OSHA / REACH)

CMR substances (Cat. 1A/1B) face restrictions under REACH Annex XVII and may be SVHC candidates. EU Directive 2004/37/EC covers carcinogens at work. OSHA 29 CFR 1910.1003–.1016 lists specific carcinogens with individual standards.

Transport marking: GHS vs ADR/DOT

GHS08 substances transported as Class 6.1 or Class 9 depending on classification. Carcinogens and mutagens may be subject to IATA DGR and IMDG Code special provisions for transport documentation and packaging.

GHS08 — Health Hazard

High-resolution SVG vector file. Free for use in safety documents, SDS, and label design.

Substances classified with GHS08

Showing 24 of 1791 substances in our database with this pictogram. View all →

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