Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

Bis(Chloromethyl) Ether

Bis(Chloromethyl) Ether is a colorless liquid with a suffocating odor.

CAS 542-88-1 C2H4Cl2O 114.96 g/mol Danger

01 · Identification

What Bis(Chloromethyl) Ether is

Bis(Chloromethyl) Ether is a colorless liquid with a suffocating odor. Its molecular formula is C2H4Cl2O and its molecular weight is 114.96 g/mol. It boils at 104 °C, melts at -41.5 °C.

Under the GHS it carries the signal word Danger. It is classed as hazardous Air Pollutants (HAPs).

CAS number542-88-1
EC number208-832-8
Index number603-046-00-5
Molecular formulaC2H4Cl2O
Molecular weight114.96 g/mol
Chemical class Hazardous Air Pollutants (HAPs)

Other names for Bis(Chloromethyl) Ether

  • oxybis(chloromethane)

02 · GHS classification

Hazards and label elements

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Signal wordDanger
Hazard statements assigned to Bis(Chloromethyl) Ether
CodeHazard statement
H225 Highly flammable liquid and vapour.
H350 May cause cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
H330 Fatal if inhaled.
H311 Toxic in contact with skin.
H302 Harmful if swallowed.

Precautionary statements: P201, P210, P233, P241, P242, P260, P270, P271, P280, P301, P302, P304, P308, P310, P312, P313, P330, P352, P403

This page lists only the codes assigned to Bis(Chloromethyl) Ether. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

03 · Physical and chemical properties

Bis(Chloromethyl) Ether properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Property Value Conditions Source
Boiling point 104 °C (219.2 °F) HSDB
106.11 °C (223 °F) at 760 mmHg CAMEO
106.11 °C (223 °F) OSHA
Melting point -41.5 °C (-42.7 °F) HSDB
-42 °C (-43.6 °F) ICSC
Density 1.3 g/cm³ ICSC
1.315 g/cm³ at 20 °C HSDB
Solubility Miscible with ethanol, ethyl ether HSDB
In water, 1,020 mg/L at 25 °C at 25 °C HSDB
In water, 2.20X10+4 mg/L at 25 °C at 25 °C HSDB
Vapor pressure 30 mmHg at 22 °C CAMEO
29.4 mmHg at 25 °C, from experimentally derived coefficients HSDB
29.2524 mmHg at 25 °C ICSC
Flash point 19 °C (66.2 °F) below this value, closed cup HSDB
18.89 °C (66 °F) below this value OSHA
19 °C (66.2 °F) below this value Haz-Map
Lower explosive limit (LEL) Forms explosive mixture with air. HSDB
Vapor density 4 (air = 1) HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

04 · Handling and storage

Storing and handling Bis(Chloromethyl) Ether

Storage conditions

PRECAUTIONS FOR "CARCINOGENS": Storage site should be as close as practicable to lab in which carcinogens are to be used, so that only small quantities required for ... expt need to be carried. Carcinogens should be kept in only one section of cupboard, an explosion-proof refrigerator or freezer (depending on chemicophysical properties ...) that bears appropriate label. An inventory ... should be kept, showing quantity of carcinogen & date it was acquired ... Facilities for dispensing ... should be contiguous to storage area. /Chemical Carcinogens/

Source: Hazardous Substances Data Bank (HSDB)

Incompatible materials

Incompatible with strong acids. ... May form shock-sensitive compounds on contact with oxidizers, peroxides, and sunlight. Attacks many plastics.

Source: Hazardous Substances Data Bank (HSDB)

Reactivity

DICHLORODIMETHYL ETHER is incompatible with the following: Acids, water [Note: Reacts with water to form hydrochloric acid & formaldehyde.] (NIOSH, 2024).

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check Bis(Chloromethyl) Ether in the storage compatibility matrix →

Safety Data Sheet

Getting an SDS for Bis(Chloromethyl) Ether

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Bis(Chloromethyl)… issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

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