Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

Build a label

Substance profile

Ethyl chloroformate

Ethyl chloroformate is a water-white liquid with a sharp, like hydrochloric acid odor.

CAS 541-41-3 Danger

01 · Identification

What Ethyl chloroformate is

Ethyl chloroformate is a water-white liquid with a sharp, like hydrochloric acid odor. It boils at 95 °C, melts at -80.6 °C.

Under the GHS it carries the signal word Danger. It is classed as corrosives.

CAS number541-41-3
EC number208-778-5
Index number607-020-00-4
Chemical class Corrosives

02 · GHS classification

Hazards and label elements

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Signal wordDanger
Hazard statements assigned to Ethyl chloroformate
CodeHazard statement
H225 Highly flammable liquid and vapour.
H330 Fatal if inhaled.
H302 Harmful if swallowed.
H314 Causes severe skin burns and eye damage.

Precautionary statements: P210, P233, P241, P242, P260, P270, P271, P280, P301, P304, P310, P312, P330, P331, P403

03 · Physical and chemical properties

Ethyl chloroformate properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Property Value Conditions Source
Boiling point 95 °C (203 °F) at 760 mmHg HSDB
93.89 °C (201 °F) at 760 mmHg CAMEO
95 °C (203 °F) ICSC
Melting point -80.6 °C (-113.1 °F) HSDB
-81.11 °C (-114 °F) CAMEO
Density 1.1 g/cm³ ICSC
1.1403 g/cm³ at 20 °C HSDB
1.135 g/cm³ at 20 °C CAMEO
Solubility PRACTICALLY INSOL & GRADUALLY DECOMP IN WATER HSDB
MISCIBLE WITH ALC, BENZENE, CHLOROFORM, ETHER HSDB
Solubility in water: reaction ICSC
Vapor pressure 41.2534 mmHg at 20 °C ICSC
22.4 mmHg at 25 °C HSDB
Flash point 16.11 °C (61 °F) HSDB
16 °C (60.8 °F) ICSC
Autoignition temperature 500 °C (932 °F) HSDB
Lower explosive limit (LEL) 3.2 % by volume decomposes ICSC
Upper explosive limit (UEL) 27.5 % by volume decomposes ICSC
Vapor density 3.7 (air = 1) HSDB
Critical temperature and pressure 235 °C (455 °F) HSDB
Corrosivity Corrosive HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

04 · Handling and storage

Storing and handling Ethyl chloroformate

Storage conditions

Store in a cool, dry, well-ventilated location. Separate from acids, alkalies, amines, alcohols, oxidizing materials, & water. Normally kept refrigerated.

Source: Hazardous Substances Data Bank (HSDB)

Incompatible materials

... WILL REACT WITH WATER OR STEAM TO PRODUCE TOXIC AND CORROSIVE FUMES; CAN REACT VIGOROUSLY WITH OXIDIZING MATERIAL.

Source: Hazardous Substances Data Bank (HSDB)

Reactivity

ETHYL CHLOROFORMATE decomposes slowly in water to form ethanol, HCl, and CO2 Attacks many metals especially in humid atmosphere [Handling Chemicals Safely 1980. p. 476]. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check Ethyl chloroformate in the storage compatibility matrix →

Get the free GHS / CLP / OSHA deadline calendar

Verified 2026–2029 compliance dates in one PDF — plus alerts when the rules change.