Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

Phosgene

Phosgene is a colorless gas with a suffocating odor; when diluted with air there is an odor reminiscent of moldy.

CAS 75-44-5 CCl2O 98.91 g/mol Danger

01 · Identification

What Phosgene is

Phosgene is a colorless gas with a suffocating odor; when diluted with air there is an odor reminiscent of moldy. Its molecular formula is CCl2O and its molecular weight is 98.91 g/mol. It boils at 8.2 °C, melts at -118 °C.

Under the GHS it carries the signal word Danger. It is classed as hazardous Air Pollutants (HAPs).

CAS number75-44-5
EC number200-870-3
Index number006-002-00-8
Molecular formulaCCl2O
Molecular weight98.91 g/mol
Chemical class Hazardous Air Pollutants (HAPs)

Other names for Phosgene

  • carbonyl chloride

02 · GHS classification

Hazards and label elements

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Signal wordDanger
Hazard statements assigned to Phosgene
CodeHazard statement
H330 Fatal if inhaled.
H314 Causes severe skin burns and eye damage.

Precautionary statements: P260, P271, P280, P301, P304, P310, P331

03 · Physical and chemical properties

Phosgene properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Property Value Conditions Source
Boiling point 8.2 °C (46.8 °F) at 760 mmHg HSDB
8.33 °C (47 °F) NIOSH
8.33 °C (47 °F) at 760 mmHg CAMEO
Melting point -118 °C (-180.4 °F) HSDB
-127.78 °C (-198 °F) NIOSH
-117.78 °C (-180 °F) CAMEO
Density 0.52 g/cm³ HSDB
1.4 g/cm³ ICSC
1.3719 g/cm³ at 25 °C HSDB
Solubility Slightly sol in water; freely sol in benzene, toluene, glacial acetic acid, and most liquid hydrocarbons HSDB
Soluble in benzene, carbon tetrachloride, chloroform, toluene, and acetic acid HSDB
Slight NIOSH
Vapor pressure 1216 mmHg NIOSH
1215 mmHg at 20 °C CAMEO
1420 mmHg at 25 °C HSDB
Autoignition temperature Not flammable (USCG, 1999) CAMEO
Lower explosive limit (LEL) Nonflammable Gas NIOSH
Vapor density 3.4 (air = 1) HSDB
Critical temperature and pressure 181.85 °C (359.3 °F) HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

04 · Source notes

Further notes on Phosgene

These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.

Corrosivity

Phosgene used in anhydrous equipment with reagents is not corrosive to ordinary metals. In presence of moisture, corrosive conditions will develop rapidly, in which case monel, tantalum, or glass lined equipment may be used.

Source: HSDB

Odor

Odor cannot be used as a warning for potential exposure. The odor threshold is reported to be between 0.5 and 1.5 parts per million (ppm) ... and tolerance to the pleasant odor of phosgene occurs rapidly.

Source: HSDB

ONE-HALF PART PER MILLION CAN BE RECOGNIZED THROUGH THE SENSE OF SMELL, BY NORMAL PERSONS ACQUAINTED WITH ITS ODOR, BUT OLFACTORY FATIGUE OR ADAPTATION CAN CAUSE A GRADUALLY INCREASING CONCENTRATION TO GO UNNOTICED.

Source: HSDB

The irritant properties of phosgene are not sufficient to give warning of hazardous concn. A trained observer can recognize 0.5 ppm as being "sweet" & at about 1 ppm, the odor becomes typical of the "musty or newmown-hay" smell usually ascribed to phosgene. Workers exposed to phosgene can lose their ability to detect low concn through olfactory fatigue.

Source: HSDB

05 · Handling and storage

Storing and handling Phosgene

Storage conditions

Phosgene must be stored to avoid contact with water, moisture, or steam since violent reactions occur. Store in tightly closed, steel containers in an isolated area away from the work area and separated form all other materials, as well as sunlight. Although phosgene in anhydrous equipment is not corrosive to ordinary metals, in presence of moisture, use monel, tantalum, or glass-lined storage containers. Phosgene should be stored away from heating and cooling ducts. Containers should be frequently inspected for leaks.

Source: Hazardous Substances Data Bank (HSDB)

Incompatible materials

Violent reaction with strong oxidizers, amines, aluminum. Attacks metals in the presence of water. Attacks plastic, rubber, and coatings.

Source: Hazardous Substances Data Bank (HSDB)

Reactivity

PHOSGENE is water reactive. Incompatible with strong oxidizing agents, alcohols, amines, alkali. May react violently with aluminum, alkali metals (lithium, potassium, sodium), alcohols (isopropyl alcohol, 2,4-hexadiyn-1,6-diol), sodium azide [Bretherick, 5th ed., 1995, p. 134]. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291]. Phosgene reacts with phosphate or silicate salts, yielding water-reactive and toxic POCl3 with phosphates (Dunlap, K.L. 2005. Phosgene. In Kirk-Othmer Encyclopedia of Chemical Technology. John Wiley & Sons, Inc.).

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check Phosgene in the storage compatibility matrix →

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