Substance profile
Methylisothiazolinone
Methylisothiazolinone is colorless prisms.
01 · Identification
What Methylisothiazolinone is
Methylisothiazolinone is colorless prisms. Its molecular formula is C4H5NOS and its molecular weight is 115.16 g/mol. It melts at 50.5 °C.
Under the GHS it carries the signal word Danger.
Other names for Methylisothiazolinone
- 2-methylisothiazol-3(2H)-one
02 · GHS classification
Hazards and label elements
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
| Code | Hazard statement |
|---|---|
| H330 | Fatal if inhaled. |
| H311 | Toxic in contact with skin. |
| H301 | Toxic if swallowed. |
| H314 | Causes severe skin burns and eye damage. |
| H318 | Causes serious eye damage. |
| H317 | May cause an allergic skin reaction. |
| H400 | Very toxic to aquatic life. |
| H410 | Very toxic to aquatic life with long lasting effects. |
Supplemental EU statements: EUH071
Precautionary statements: P260, P261, P270, P271, P272, P273, P280, P301, P302, P304, P305, P310, P313, P330, P331, P333, P338, P352, P391, P501
03 · Physical and chemical properties
Methylisothiazolinone properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 93 °C (199.4 °F) | at 0.03 mmHg (reduced pressure) | HSDB |
| Melting point | 50.5 °C (122.9 °F) | range, midpoint shown | HSDB |
| Density | 1.19 g/cm³ | at 20 °C | HSDB |
| 1.35 g/cm³ | at 25 °C | HSDB | |
| Solubility | Solubility in: acetonitrile 78.6; methanol 79.1; hexane 2.371; xylenol 15.65 (g/100 mL) | HSDB | |
| Vapor pressure | 0.062 mmHg | at 25 °C | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
04 · Handling and storage
Storing and handling Methylisothiazolinone
Storage conditions
Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Source: Hazardous Substances Data Bank (HSDB)
Incompatible materials
Materials to avoid: Strong oxidizing agents, Amines, Mercaptans, Reducing agents.
Source: Hazardous Substances Data Bank (HSDB)
Planning storage for a mix of chemicals? Check Methylisothiazolinone in the storage compatibility matrix →