Substance profile
2,2'-bioxirane
2,2'-bioxirane is a water-white.
01 · Identification
What 2,2'-bioxirane is
2,2'-bioxirane is a water-white. It boils at 138 °C, melts at -19 °C.
Under the GHS it carries the signal word Danger. It is classed as carcinogens.
Other names for 2,2'-bioxirane
- 1,2:3,4-diepoxybutane
02 · GHS classification
Hazards and label elements
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
| Code | Hazard statement |
|---|---|
| H350 | May cause cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H340 | May cause genetic defects <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H330 | Fatal if inhaled. |
| H311 | Toxic in contact with skin. |
| H301 | Toxic if swallowed. |
| H314 | Causes severe skin burns and eye damage. |
Precautionary statements: P201, P260, P270, P271, P280, P301, P302, P304, P308, P310, P313, P330, P331, P352
03 · Physical and chemical properties
2,2'-bioxirane properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 138 °C (280.4 °F) | HSDB | |
| 143.89 °C (291 °F) | at 760 mmHg | CAMEO | |
| 137.78 °C (280 °F) | at 760 mmHg | CAMEO | |
| Melting point | -19 °C (-2.2 °F) | HSDB | |
| 3.89 °C (39 °F) | CAMEO | ||
| 19 °C (66.2 °F) | DOE PAC | ||
| Density | 0.962 g/cm³ | HSDB | |
| 1.1157 g/cm³ | at 20 °C | CAMEO | |
| 1.113 g/cm³ | at 18 °C | CAMEO | |
| Solubility | In water, 1X10+6 mg/l | HSDB | |
| greater than or equal to 100 mg/mL at 67.1 °F (NTP, 1992) | at 19.5 °C | CAMEO | |
| Vapor pressure | 3.9 mmHg | at 20 °C | HSDB |
| 16 mmHg | at 25 °C | DOE PAC | |
| Flash point | 45.56 °C (114 °F) | CAMEO |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
04 · Handling and storage
Storing and handling 2,2'-bioxirane
Storage conditions
PRECAUTIONS FOR "CARCINOGENS": Storage site should be as close as practical to lab in which carcinogens are to be used, so that only small quantities required for ... expt need to be carried. Carcinogens should be kept in only one section of cupboard, an explosion-proof refrigerator or freezer (depending on chemicophysical properties ...) that bears appropriate label. An inventory ... should be kept, showing quantity of carcinogen & date it was acquired ... Facilities for dispensing ... should be contiguous to storage area. /Chemical Carcinogens/
Source: Hazardous Substances Data Bank (HSDB)
Reactivity
D,L-1,2:3,4-DIEPOXYBUTANE is incompatible with acids, bases and oxidizing agents. Reacts with 4-(4'-nitrobenzyl)pyridine. Also reacts with alcohols, amines, phenols. (NTP, 1992)
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check 2,2'-bioxirane in the storage compatibility matrix →