Substance profile
P-Anisidine
P-Anisidine is a white solid with an amine-like odor.
01 · Identification
What P-Anisidine is
P-Anisidine is a white solid with an amine-like odor. Its molecular formula is C7H9NO and its molecular weight is 123.15 g/mol. It boils at 243 °C, melts at 57.2 °C, is soluble in water.
Under the GHS it carries the signal word Danger.
Other names for P-Anisidine
- 4-methoxyaniline
02 · GHS classification
Hazards and label elements
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
| Code | Hazard statement |
|---|---|
| H310 | Fatal in contact with skin. |
| H330 | Fatal if inhaled. |
| H300 | Fatal if swallowed. |
| H373 | May cause damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H400 | Very toxic to aquatic life. |
Precautionary statements: P260, P270, P271, P273, P280, P301, P302, P304, P310, P314, P330, P352, P391, P501
03 · Physical and chemical properties
P-Anisidine properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 243 °C (469.4 °F) | HSDB | |
| 246.11 °C (475 °F) | NIOSH | ||
| 242.78 °C (469 °F) | at 760 mmHg | CAMEO | |
| Melting point | 57.2 °C (135 °F) | HSDB | |
| 57.22 °C (135 °F) | NIOSH | ||
| Density | 1.07 g/cm³ | NIOSH | |
| 1.071 g/cm³ | at 57 °C | HSDB | |
| Solubility | Soluble in acetone, benzene; very soluble in ether, ethanol | HSDB | |
| Moderate | NIOSH | ||
| In water, 2.10X10+4 mg/L at 20 °C | at 20 °C | HSDB | |
| Vapor pressure | 0.03 mmHg | at 20 °C | HSDB |
| 0.015 mmHg | at 20 °C | ICSC | |
| 0.006 mmHg | at 25 °C | NIOSH | |
| Flash point | 122 °C (251.6 °F) | HSDB | |
| 5 °C (41 °F) | CAMEO | ||
| Autoignition temperature | 515 °C (959 °F) | HSDB | |
| Lower explosive limit (LEL) | Finely dispersed particles form explosive mixtures in air. | HSDB | |
| Combustible Solid | NIOSH | ||
| Vapor density | 4.28 (air = 1) | HSDB | |
| 4.25 (air = 1) | CAMEO | ||
| 4.3 (air = 1) | ICSC |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
04 · Handling and storage
Storing and handling P-Anisidine
Storage conditions
Store in tightly closed containers in a cool, dark, well-ventilated area. Protect against sunlight and strong oxidizers. Metal containers involving the transfer of this chemical should be grounded and bonded. Where possible, automatically pump liquid from drums or other storage containers to process containers. Drums must be equipped with self-closing valves, pressure vacuum bungs, and flame arresters. Use only non-sparking tools and equipment, especially when opening and closing containers of this chemical. Sources of ignition, such as smoking and open flames, are prohibited where this chemical is used, handled, or stored in a manner that could create a potential fire or explosion hazard. A regulated, marked area should be established where this chemical is handled, used, or stored ... /Anisidines/
Source: Hazardous Substances Data Bank (HSDB)
Incompatible materials
Incompatible with strong oxidizers, with risk of fire or explosions. Attacks some coatings and some forms of plastic and rubber. /Anisidines/
Source: Hazardous Substances Data Bank (HSDB)
Reactivity
P-ANISIDINE may be sensitive to heat, light and moisture. Reacts with acids, acid chlorides, acid anhydrides, chloroformates and strong oxidizing agents. Incompatible with alkaline materials. Incompatible with aldehydes, ketones and nitrates. (NTP, 1992)
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check P-Anisidine in the storage compatibility matrix →