Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

Trichloronitromethane

Trichloronitromethane is a slightly oily liquid with an intensely irritating tear gas odor.

CAS 76-06-2 CCl3NO2 164.37 g/mol Danger

01 · Identification

What Trichloronitromethane is

Trichloronitromethane is a slightly oily liquid with an intensely irritating tear gas odor. Its molecular formula is CCl3NO2 and its molecular weight is 164.37 g/mol. It boils at 112 °C, melts at -64 °C, is miscible with water.

Under the GHS it carries the signal word Danger. It is classed as reactive agents - 3rd degree.

CAS number76-06-2
EC number200-930-9
Index number610-001-00-3
Molecular formulaCCl3NO2
Molecular weight164.37 g/mol
Chemical class Reactive agents - 3rd degree

Other names for Trichloronitromethane

  • chloropicrin

02 · GHS classification

Hazards and label elements

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Signal wordDanger
Hazard statements assigned to Trichloronitromethane
CodeHazard statement
H330 Fatal if inhaled.
H302 Harmful if swallowed.
H335 May cause respiratory irritation.
H315 Causes skin irritation.
H319 Causes serious eye irritation.

Precautionary statements: P260, P264, P270, P271, P280, P301, P302, P304, P305, P310, P312, P313, P330, P332, P337, P338, P352

03 · Physical and chemical properties

Trichloronitromethane properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Property Value Conditions Source
Boiling point 112 °C (233.6 °F) at 757 mmHg HSDB
112.22 °C (234 °F) NIOSH
112.22 °C (234 °F) at 760 mmHg CAMEO
Melting point -64 °C (-83.2 °F) HSDB
-69.44 °C (-93 °F) NIOSH
-69.22 °C (-92.6 °F) CAMEO
Density 1.66 g/cm³ NIOSH
1.6448 g/cm³ at 20 °C HSDB
1.64 g/cm³ at 25 °C CAMEO
Solubility Miscible with most organic solvents, e.g. acetone, benzene, ethanol, methanol, carbon disulfide, diethyl ether, carbon tetrachloride HSDB
Miscible with absolute alcohol; soluble in ether HSDB
Miscible with acetic acid HSDB
Vapor pressure 18 mmHg NIOSH
16.9 mmHg at 20 °C CAMEO
24.002 mmHg at 25 °C HSDB
Lower explosive limit (LEL) Not combustible, but material if contaminated may explode when heated under confinement. Closed containers may rupture violently when heated. HSDB
Vapor density 5.7 (air = 1) HSDB
Odor threshold Threshold odor concn: 1.1 ppm HSDB
Faint odor at 0.0073 mg/L HSDB
Corrosivity RELATIVELY INERT CHEMICALLY & NON-CORROSIVE TO COPPER, BRASS & BRONZE BUT ATTACKS IRON, ZINC & OTHER LIGHT METALS HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

04 · Fire and explosion

Fire and explosion behaviour of Trichloronitromethane

These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.

Fire and explosion

During addition of the nitrocompound in methanol to sodium methoxide solution, the temperature must not be allowed to fall much below 50 °C. If this happens , excess nitro compound will accumulate and cause a violent and dangerous exotherm.

Source: HSDB

An insecticidal mixture in a rail tank exploded with great violence during pump transfer operations, possibly owing to the pump running dry and overheating. Both components of the mixture are explosive and the mixture was also found to be shock and heat sensitive.

Source: HSDB

Odor

The odor threshold is reportedly 0.78 ppm for chloropicrin. Definitive exposure-response data for humans comes from sensory irritation studies conducted with human volunteers. More sensitive individuals exposed for 20-30 minutes reported chloropicrin concentration of 150 ppb (0.150 ppm) to be detectable as determined by notable ocular and nasal irritation. Exposure to 50 ppb (0.050 ppm) was reported as a No- Observed-Adverse-Effect-Level (NOAEL) for volunteer subjects (males and females; ages 18-35 years and including sensitive individuals).

Source: HSDB

05 · Handling and storage

Storing and handling Trichloronitromethane

Storage conditions

Store in a cool, dry, well-ventilated location. Separate from oxidizing materials. Outside or detached storage is preferred.

Source: Hazardous Substances Data Bank (HSDB)

Incompatible materials

Incompatible with strong oxidizers.

Source: Hazardous Substances Data Bank (HSDB)

Reactivity

CHLOROPICRIN is a powerful irritant affecting all body surfaces, more toxic then chlorine. It can be shocked into detonation. When heated to decomposition, it emits highly toxic fumes of chlorine gas and nitrogen oxides [Sax, 9th ed., 1996, p. 821]. It produces a violent reaction with aniline [Jackson, K. E., Chem. Rev., 1934, 14, p. 269] or strong bases in the presence of alcohols (alkoxides) [Ramsey, B. G., et al., J. Am. Chem. Soc., 1966, 88, p. 3059]. An insecticidal mixture of the nitrocompound and 3-bromopropyne exploded violently, initiated by an overheated pump during a railcar transfer operation, [BCISC Quart. Safety Summ., 1968, 39, 12].

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check Trichloronitromethane in the storage compatibility matrix →

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