Substance profile
1-Chloro-4-nitrobenzene
1-Chloro-4-nitrobenzene is monoclinic prisms with a sweet odor.
01 · Identification
What 1-Chloro-4-nitrobenzene is
1-Chloro-4-nitrobenzene is monoclinic prisms with a sweet odor. Its molecular formula is C6H4ClNO2 and its molecular weight is 157.55 g/mol. It boils at 242 °C, melts at 83.3 °C, is soluble in water.
Under the GHS it carries the signal word Danger. It is classed as reactive agents - 3rd degree.
02 · GHS classification
Hazards and label elements
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
| Code | Hazard statement |
|---|---|
| H351 | Suspected of causing cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H341 | Suspected of causing genetic defects <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H331 | Toxic if inhaled. |
| H311 | Toxic in contact with skin. |
| H301 | Toxic if swallowed. |
| H373 | May cause damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H411 | Toxic to aquatic life with long lasting effects. |
Precautionary statements: P201, P260, P270, P271, P273, P280, P301, P302, P304, P308, P310, P313, P314, P330, P352, P391, P501
03 · Physical and chemical properties
1-Chloro-4-nitrobenzene properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 242 °C (467.6 °F) | at 760 mmHg | HSDB |
| 242.22 °C (468 °F) | NIOSH | ||
| 242.22 °C (468 °F) | at 760 mmHg | CAMEO | |
| Melting point | 83.33 °C (182 °F) | NIOSH | |
| 83.61 °C (182.5 °F) | CAMEO | ||
| Density | 1.52 g/cm³ | HSDB | |
| 1.3 g/cm³ | ICSC | ||
| Solubility | Sparingly sol in cold alc and freely in boiling alcohol, ether, carbon disulfide. | HSDB | |
| Soluble in organic solvents | HSDB | ||
| In water, 225 mg/L at 20 °C | at 20 °C | HSDB | |
| Vapor pressure | 0.0219 mmHg | at 25 °C | HSDB |
| 0.09 mmHg | at 25 °C | CAMEO | |
| 0.2 mmHg | at 30 °C | NIOSH | |
| Flash point | 127.22 °C (261 °F) | HSDB | |
| Autoignition temperature | 510 °C (950 °F) | ICSC | |
| Lower explosive limit (LEL) | Solid that does not burn, or burns with difficulty. | NIOSH | |
| Vapor density | 5.44 (air = 1) | HSDB | |
| Critical temperature and pressure | 477.85 °C (892.1 °F) | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
04 · Handling and storage
Storing and handling 1-Chloro-4-nitrobenzene
Storage conditions
Store in cool, dry, well-ventilated location. Separate from alkalies and oxidizing materials. /Chloronitrobenzenes/
Source: Hazardous Substances Data Bank (HSDB)
Incompatible materials
A strong oxidizer. Reacts violently with oxidizers, combustibles, alkalis, sodium methoxide, and reducing materials.
Source: Hazardous Substances Data Bank (HSDB)
Reactivity
P-NITROCHLOROBENZENE reacts with oxidizing agents. Reacts violently and finally explosively when added to a solution of sodium methoxide in methanol. (NTP, 1992). Unstable when heated.
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check 1-Chloro-4-nitrobenzene in the storage compatibility matrix →