Substance profile
Cycloheximide
Cycloheximide is plates from amyl acetate, water or 30% methanol.
01 · Identification
What Cycloheximide is
Cycloheximide is plates from amyl acetate, water or 30% methanol. It melts at 25 °C.
Under the GHS it carries the signal word Danger. It is classed as teratogens.
Other names for Cycloheximide
- cycloheximide (ISO)
- 4-{}{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}}piperidine-2,6-dione
02 · GHS classification
Hazards and label elements
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
| Code | Hazard statement |
|---|---|
| H341 | Suspected of causing genetic defects <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H360D | May damage the unborn child. |
| H300 | Fatal if swallowed. |
| H411 | Toxic to aquatic life with long lasting effects. |
Precautionary statements: P201, P270, P273, P280, P301, P308, P310, P313, P330, P391, P501
03 · Physical and chemical properties
Cycloheximide properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 25 °C (77 °F) | Cycloheximide acetate | HSDB |
| 120.25 °C (248.5 °F) | range, midpoint shown | HSDB | |
| 120.28 °C (248.5 °F) | range, midpoint shown | CAMEO | |
| Solubility | INSOL IN PETROLEUM ETHER | HSDB | |
| Isopropyl alcohol 5.5 g/100 ml; acetone 33.0 g/100 ml; cyclohexanone 19.0 g/100 ml (@ 20 °C) | at 20 °C | HSDB | |
| In water, 2.1X10-4 mg/l @ 25 °C | at 25 °C | HSDB | |
| Vapor pressure | 0.006 mmHg | at 25 °C | DOE PAC |
| Corrosivity | NONCORROSIVE | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
04 · Handling and storage
Storing and handling Cycloheximide
Reactivity
CYCLOHEXIMIDE is an imide. This chemical is incompatible with strong oxidizing agents, acid chlorides and acid anhydrides. It decomposes rapidly in alkali at room temperature. (NTP, 1992)
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check Cycloheximide in the storage compatibility matrix →