Substance profile
Mephosfolan
Mephosfolan is a colorless liquid.
01 · Identification
What Mephosfolan is
Mephosfolan is a colorless liquid. Its molecular formula is C8H16NO3PS2 and its molecular weight is 269.3 g/mol. It boils at 410 °C.
Under the GHS it carries the signal word Danger.
Other names for Mephosfolan
- mephosfolan (ISO)
- diethyl 4-methyl-1,3-dithiolan-2-ylidenephosphoramidate
02 · GHS classification
Hazards and label elements
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
| Code | Hazard statement |
|---|---|
| H310 | Fatal in contact with skin. |
| H300 | Fatal if swallowed. |
| H411 | Toxic to aquatic life with long lasting effects. |
Precautionary statements: P270, P273, P280, P301, P302, P310, P330, P352, P391, P501
03 · Physical and chemical properties
Mephosfolan properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 410 °C (770 °F) | at 760 mmHg | DOE PAC |
| 120 °C (248 °F) | at 0.001 mmHg (reduced pressure) | HSDB | |
| Density | 1.539 g/cm³ | at 26 °C | HSDB |
| Solubility | Soluble in acetone, xylene, benzene, ethanol and toluene, moderately soluble in water. | HSDB | |
| Solubility in water at 25 °C: 57 g/kg. | at 25 °C | HSDB | |
| Vapor pressure | 1e-10 mmHg | at 25 °C | DOE PAC |
| 0.0000318 mmHg | Haz-Map |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
04 · Handling and storage
Storing and handling Mephosfolan
Reactivity
When heated to decomposition, MEPHOSFOLAN emits very toxic fumes of nitrogen oxides, phosphorus oxides and sulfur oxides. Stable at neutral pH. Hydrolyzed by acid or alkali. [EPA, 1998]. Organophosphates, such as MEPHOSFOLAN, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check Mephosfolan in the storage compatibility matrix →