Substance profile
Fluoroacetamide
Fluoroacetamide is a colorless crystalline powder.
01 · Identification
What Fluoroacetamide is
Fluoroacetamide is a colorless crystalline powder. Its molecular formula is C2H4FNO and its molecular weight is 77.06 g/mol. It boils at 250 °C, melts at 108 °C.
Under the GHS it carries the signal word Danger.
Other names for Fluoroacetamide
- 2-fluoroacetamide
02 · GHS classification
Hazards and label elements
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
| Code | Hazard statement |
|---|---|
| H300 | Fatal if swallowed. |
| H311 | Toxic in contact with skin. |
Precautionary statements: P270, P280, P301, P302, P310, P330, P352
03 · Physical and chemical properties
Fluoroacetamide properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 250 °C (482 °F) | at 760 mmHg | DOE PAC |
| Sublimes | sublimes | HSDB | |
| Sublimes on heating (EPA, 1998) | sublimes | CAMEO | |
| Melting point | 108 °C (226.4 °F) | HSDB | |
| 107 °C (224.6 °F) | ICSC | ||
| 108.06 °C (226.5 °F) | range, midpoint shown | CAMEO | |
| Solubility | Freely sol in water, sol in acetone; sparingly sol in chloroform | HSDB | |
| Moderately sol in ethanol; sparingly sol in aliphatic and aromatic hydrocarbons | HSDB | ||
| Solubility in water: very good | ICSC | ||
| Vapor pressure | 0.001 mmHg | at 25 °C | DOE PAC |
| 0.99 mmHg | Haz-Map |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
04 · Handling and storage
Storing and handling Fluoroacetamide
Storage conditions
STORE IN CLOSED CONTAINERS IN CLOSED AREA.
Source: Hazardous Substances Data Bank (HSDB)
Reactivity
FLUOROACETAMIDE is a fluorinated amide. Organic amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check Fluoroacetamide in the storage compatibility matrix →