Substance profile
4-Methylpyridine
4-Methylpyridine is a colorless liquid with obnoxious, sweetish odor.
01 · Identification
What 4-Methylpyridine is
4-Methylpyridine is a colorless liquid with obnoxious, sweetish odor. Its molecular formula is C6H7N and its molecular weight is 93.13 g/mol. It boils at 145 °C, melts at 3.7 °C, is miscible with water.
Under the GHS it carries the signal word Danger.
Other names for 4-Methylpyridine
- 4-picoline
02 · GHS classification
Hazards and label elements
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
| Code | Hazard statement |
|---|---|
| H226 | Flammable liquid and vapour. |
| H311 | Toxic in contact with skin. |
| H332 | Harmful if inhaled. |
| H302 | Harmful if swallowed. |
| H335 | May cause respiratory irritation. |
| H315 | Causes skin irritation. |
| H319 | Causes serious eye irritation. |
Precautionary statements: P210, P233, P241, P242, P260, P264, P270, P271, P280, P301, P302, P304, P305, P310, P312, P313, P330, P332, P337, P338, P352, P403
03 · Physical and chemical properties
4-Methylpyridine properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 145 °C (293 °F) | at 760 mmHg | HSDB |
| 144.89 °C (292.8 °F) | at 760 mmHg | CAMEO | |
| 144.5 °C (292.1 °F) | range, midpoint shown | ICSC | |
| Melting point | 3.68 °C (38.6 °F) | HSDB | |
| 3.61 °C (38.5 °F) | CAMEO | ||
| 3.7 °C (38.7 °F) | ICSC | ||
| Density | 0.96 g/cm³ | ICSC | |
| 0.9548 g/cm³ | at 20 °C | HSDB | |
| Solubility | Soluble in alcohol, ether | HSDB | |
| Soluble in acetone, carbon tetrachloride | HSDB | ||
| Miscible with water at 20 °C | at 20 °C | HSDB | |
| Vapor pressure | 5.77 mmHg | at 25 °C | HSDB |
| 5.7005 mmHg | at 25 °C | ICSC | |
| 5.77 mmHg | Haz-Map | ||
| Flash point | 56.67 °C (134 °F) | HSDB | |
| 39 °C (102.2 °F) | HSDB | ||
| Lower explosive limit (LEL) | 1.3 % by volume | ICSC | |
| Upper explosive limit (UEL) | 8.7 % by volume | ICSC | |
| Vapor density | 3.2 (air = 1) | HSDB | |
| Critical temperature and pressure | 372.65 °C (702.8 °F) | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
04 · Handling and storage
Storing and handling 4-Methylpyridine
Storage conditions
Conditions for safe storage, including any incompatibilities: Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Source: Hazardous Substances Data Bank (HSDB)
Incompatible materials
Incompatible materials: Oxidizing agents.
Source: Hazardous Substances Data Bank (HSDB)
Reactivity
4-METHYL PYRIDINE neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check 4-Methylpyridine in the storage compatibility matrix →