Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

2-ethoxyethanol

2-ethoxyethanol is a colorless liquid with a sweet, pleasant, ether-like odor.

CAS 110-80-5 C4H10O2 90.12 g/mol Danger

01 · Identification

What 2-ethoxyethanol is

2-ethoxyethanol is a colorless liquid with a sweet, pleasant, ether-like odor. Its molecular formula is C4H10O2 and its molecular weight is 90.12 g/mol. It boils at 136 °C, melts at -70 °C, is miscible with water.

Under the GHS it carries the signal word Danger. It is classed as teratogens.

CAS number110-80-5
EC number203-804-1
Index number603-012-00-X
Molecular formulaC4H10O2
Molecular weight90.12 g/mol
Chemical class Teratogens

Other names for 2-ethoxyethanol

  • ethylene glycol monoethyl ether

02 · GHS classification

Hazards and label elements

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Signal wordDanger
Hazard statements assigned to 2-ethoxyethanol
CodeHazard statement
H226 Flammable liquid and vapour.
H360FD May damage fertility. May damage the unborn child.
H331 Toxic if inhaled.
H302 Harmful if swallowed.

Precautionary statements: P210, P233, P241, P242, P260, P270, P271, P301, P304, P310, P312, P330, P403

03 · Physical and chemical properties

2-ethoxyethanol properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Property Value Conditions Source
Boiling point 135.7 °C (276.3 °F) HSDB
135 °C (275 °F) NIOSH
135 °C (275 °F) at 760 mmHg CAMEO
Melting point -70 °C (-94 °F) HSDB
-90 °C (-130 °F) NIOSH
Density 0.93 g/cm³ NIOSH
7.74 g/cm³ at 20 °C HSDB
0.9253 g/cm³ at 25 °C HSDB
Solubility Miscible with water HSDB
Very soluble in acetone, ethyl ether, ethanol HSDB
Miscible with hydrocarbons HSDB
Vapor pressure 4 mmHg NIOSH
3.8 mmHg at 20 °C CAMEO
5.31 mmHg at 25 °C HSDB
Flash point 43.33 °C (110 °F) HSDB
48.89 °C (120 °F) HSDB
94.44 °C (202 °F) HSDB
Autoignition temperature 235 °C (455 °F) HSDB
Lower explosive limit (LEL) 1.8 % by volume CAMEO
1.7 % by volume DOE PAC
Upper explosive limit (UEL) 14 % by volume CAMEO
15.6 % by volume at 93 °C HSDB
Vapor density 3.1 (air = 1) CAMEO
Odor threshold ...Odor threshold of about 25 ppm and a strong odor at about 50 ppm. HSDB
Odor Threshold Low: 0.3 [ppm] Haz-Map

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

04 · Source notes

Further notes on 2-ethoxyethanol

These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.

Odor

Human volunteers with some work experience in industrial environments reported that /odor/ levels of 125 ppm were noticeable and that the intolerable odor level was higher then 255 ppm. Thus the warning properties should not be relied up on to prevent prolonged daily exposures to a concentration of vapors that could cause adverse affects.

Source: HSDB

05 · Handling and storage

Storing and handling 2-ethoxyethanol

Storage conditions

Conditions for safe storage: Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.

Source: Hazardous Substances Data Bank (HSDB)

Incompatible materials

Polyacrylamide gels were dissolved in 30% peroxide solution and added to a scintillation mixture in 1:1 2-ethoxyethanol-toluene. After counting, the mixtures were bulked and evaporated intermittently with heat during a 4 week period, and the accumulated peroxidised residues eventually exploded violently. A subsequent comment indicated that peroxidised materials may not peroxide are themselves potentially explosive.

Source: Hazardous Substances Data Bank (HSDB)

Reactivity

ETHYLENE GLYCOL MONOETHYL ETHER may react with oxidizing materials, i.e. hydrogen peroxide, to form peroxides. It dissolves many oils, resins and waxes. (NTP, 1992)

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check 2-ethoxyethanol in the storage compatibility matrix →

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