Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

Hexane

Hexane is a liquid with a gasoline-like odor.

CAS 110-54-3 Danger

Hexane Safety Data Sheet →

01 · Identification

What Hexane is

Hexane is a liquid with a gasoline-like odor. It boils at 68.7 °C, melts at -95.3 °C.

Under the GHS it carries the signal word Danger. It is classed as hazardous Air Pollutants (HAPs).

CAS number110-54-3
EC number203-777-6
Index number601-037-00-0
Chemical class Hazardous Air Pollutants (HAPs)

Other names for Hexane

  • n-hexane
  • C6H14
  • Dipropyl
  • Gettysolve-B
  • Hexane (N)
  • Hexanes
  • Hexyl Hydride
  • Normal Hexane
  • Normal-Hexane
  • Skellysolve B

02 · GHS classification

Hazards and label elements

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Signal wordDanger
Hazard statements assigned to Hexane
CodeHazard statement
H225 Highly flammable liquid and vapour.
H361f Suspected of damaging fertility.
H304 May be fatal if swallowed and enters airways.
H336 May cause drowsiness or dizziness.
H372 Causes damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
H315 Causes skin irritation.
H411 Toxic to aquatic life with long lasting effects.

Precautionary statements: P210, P233, P241, P242, P260, P264, P270, P273, P280, P302, P313, P314, P332, P352, P391, P403, P501

03 · Physical and chemical properties

Hexane properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Property Value Conditions Source
Boiling point 68.73 °C (155.7 °F) HSDB
68.89 °C (156 °F) NIOSH
68.89 °C (156 °F) at 760 mmHg CAMEO
Melting point -95.35 °C (-139.6 °F) HSDB
-139.44 °C (-219 °F) NIOSH
-95 °C (-139 °F) CAMEO
Density 0.66 g/cm³ NIOSH
0.659 g/cm³ at 20 °C CAMEO
0.6606 g/cm³ at 25 °C HSDB
Solubility Very soluble in ethanol; soluble in ethyl ether, chloroform HSDB
9.5 to 13 mg/L at 20 °C in distilled water, 75.5 mg/L at 20 °C in salt water at 20 °C HSDB
In water, 9.5 mg/L at 25 °C at 25 °C HSDB
Vapor pressure 124 mmHg NIOSH
120 mmHg at 20 °C HSDB
153 mmHg at 25 °C HSDB
Flash point -21.67 °C (-7 °F) HSDB
-23 °C (-9.4 °F) CAMEO
Autoignition temperature 225 °C (437 °F) HSDB
Lower explosive limit (LEL) 1.1 % by volume by volume HSDB
1.1 % by volume NIOSH
1.2 % by volume CAMEO
Upper explosive limit (UEL) 7.5 % by volume by volume HSDB
7.5 % by volume NIOSH
Vapor density 2.97 (air = 1) HSDB
3 (air = 1) ICSC
Odor threshold 0.0064 mg/l HSDB
Odor Threshold Low: 65.0 [ppm] Haz-Map
Odor Threshold High: 248.0 [ppm] Haz-Map
Critical temperature and pressure 234.35 °C (453.8 °F) HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

04 · Handling and storage

Storing and handling Hexane

Storage conditions

Drums should be stored in a well-ventilated area in fire-resistant containers. Metal containers should be electrically-grounded, when liquid is being transferred.

Source: Hazardous Substances Data Bank (HSDB)

Incompatible materials

Forms explosive mixture with air. Contact with strong oxidizers may cause fire and explosions. contact with dinitrogen tetreoxide may explode at 28 °C. Attacks some plastics, rubber and coatings. may accumulate static electrical charges, and may cause ignition of its vapor.

Source: Hazardous Substances Data Bank (HSDB)

Reactivity

N-HEXANE may be sensitive to light. It may also be sensitive to prolonged exposure to heat. This compound can react vigorously with oxidizing materials. This would include compounds such as liquid chlorine, concentrated O2, sodium hypochlorite and calcium hypochlorite. It is also incompatible with dinitrogen tetraoxide. It will attack some forms of plastics, rubber and coatings. (NTP, 1992).

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check Hexane in the storage compatibility matrix →

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