Substance profile
4-chloro-o-cresol
4-chloro-o-cresol is needles from petroleum ether with a mild, phenolic odor.
01 · Identification
What 4-chloro-o-cresol is
4-chloro-o-cresol is needles from petroleum ether with a mild, phenolic odor. It boils at 223 °C, melts at 51 °C.
Under the GHS it carries the signal word Danger.
Other names for 4-chloro-o-cresol
- 4-chloro-2-methyl phenol
02 · GHS classification
Hazards and label elements
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
| Code | Hazard statement |
|---|---|
| H331 | Toxic if inhaled. |
| H314 | Causes severe skin burns and eye damage. |
| H400 | Very toxic to aquatic life. |
Precautionary statements: P260, P271, P273, P280, P301, P304, P310, P331, P391, P501
This page lists only the codes assigned to 4-chloro-o-cresol. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
03 · Physical and chemical properties
4-chloro-o-cresol properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 223 °C (433.4 °F) | HSDB | |
| 231 °C (447.8 °F) | ICSC | ||
| 223.61 °C (434.5 °F) | range, midpoint shown, at 760 mmHg | CAMEO | |
| Melting point | 51 °C (123.8 °F) | HSDB | |
| 49.44 °C (121 °F) | range, midpoint shown | CAMEO | |
| 48 °C (118.4 °F) | range, midpoint shown | ICSC | |
| Density | 1.2 g/cm³ | HSDB | |
| 0.48 g/cm³ | ICSC | ||
| Solubility | Sol in petroleum ether | HSDB | |
| Solubility in water, g/100ml at 20 °C: 0.23 | at 20 °C | ICSC | |
| In water, 4.00X10+3 mg/l @ 25 °C | at 25 °C | HSDB | |
| Vapor pressure | 0.2025 mmHg | at 20 °C | ICSC |
| 0.024 mmHg | at 25 °C | HSDB | |
| 0.02 mmHg | Haz-Map | ||
| Flash point | 112.78 °C (235 °F) | above this value | CAMEO |
| 78 °C (172.4 °F) | Haz-Map | ||
| Odor threshold | Odor detection threshold= 1,800 ug/l at 20-22 °C | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
04 · Handling and storage
Storing and handling 4-chloro-o-cresol
Incompatible materials
A large quantitiy (700 kg) of /4-chloro-2-methylphenol/, left in contact with concentrated sodium hydroxide soln for 3 days, decomposed, attaining red heat and evolving fumes which ignited explosively. Although this could not be reproduced under laboratory conditions, it is believed that exothermic hydrolysis to the hydroquinone (possibly with subsequent aerobic oxidation to the quinone) occurred, the high viscosity of the liquid preventing dissipation of heat.
Source: Hazardous Substances Data Bank (HSDB)
Reactivity
P-CHLORO-O-CRESOL can react vigorously with concentrated sodium hydroxide solutions. Also reacts with other bases, acid chlorides, acid anhydrides, and oxidizing agents. Corrodes steel, brass, copper and copper alloys [NTP, 1992)]. A large quantity left in contact with concentrated sodium hydroxide solution for 3 days reacted violently, attaining red heat and evolving fumes that ignited explosively. The heat of reaction dissipated poorly because of the high viscosity of the mixture [Quart. Safety Summ., 1957, 28, 39].
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check 4-chloro-o-cresol in the storage compatibility matrix →
Safety Data Sheet
Getting an SDS for 4-chloro-o-cresol
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of 4-chloro-o-cresol issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
Nearby
Substances next to 4-chloro-o-cresol
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