Substance profile
4-Aminophenol
4-Aminophenol is orthorhombic plates from water.
01 · Identification
What 4-Aminophenol is
4-Aminophenol is orthorhombic plates from water. It boils at 284 °C, melts at 188 °C.
Under the GHS it carries the signal word Warning.
02 · GHS classification
Hazards and label elements
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
| Code | Hazard statement |
|---|---|
| H341 | Suspected of causing genetic defects <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H332 | Harmful if inhaled. |
| H302 | Harmful if swallowed. |
| H400 | Very toxic to aquatic life. |
| H410 | Very toxic to aquatic life with long lasting effects. |
Precautionary statements: P201, P260, P270, P271, P273, P280, P301, P304, P308, P312, P313, P330, P391, P501
03 · Physical and chemical properties
4-Aminophenol properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 284 °C (543.2 °F) | decomposes, at 760 mmHg | HSDB |
| 283.89 °C (543 °F) | decomposes, at 760 mmHg | CAMEO | |
| 110 °C (230 °F) | decomposes, at 0.3 mmHg (reduced pressure) | HSDB | |
| Melting point | 187.5 °C (369.5 °F) | HSDB | |
| 186.67 °C (368 °F) | range, midpoint shown | CAMEO | |
| 187.5 °C (369.5 °F) | at 760 mmHg | HMDB | |
| Density | 1.29 g/cm³ | alpha-4-Aminophenol | HSDB |
| Solubility | Slightly soluble in toluene, diethyl ether, ethanol, cold water; soluble in acetonitrile, ethyl acetate, acetone, hot water; very soluble in dimethylsulfoxide. | HSDB | |
| Very soluble in ethanol; insoluble in benzene, chloroform; slightly soluble in trifluoroacetic acid; soluble in alkalies | HSDB | ||
| In water, 1.6X10+3 mg/L at 20 °C | at 20 °C | HSDB | |
| Vapor pressure | 0.00004 mmHg | at 25 °C | HSDB |
| 0.00004 mmHg | Haz-Map | ||
| Flash point | 195 °C (383 °F) | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
04 · Handling and storage
Storing and handling 4-Aminophenol
Storage conditions
Store in tightly closed containers in a cool, well-ventilated area. Aminophenols must be stored to avoid contact with strong oxidizers (such as chlorine, bromine, and fluorine), since violent reactions occur. /Aminophenols/
Source: Hazardous Substances Data Bank (HSDB)
Incompatible materials
Strong oxidants. /Aminophenols/
Source: Hazardous Substances Data Bank (HSDB)
Reactivity
P-AMINOPHENOL is sensitive to: Heat (decomposition forming HCN, nitrous vapors, CO); water (CO2); reacts violently with acids, bases, alcohols and amines causing fire and explosion hazards [Handling Chemicals Safely 1980 p. 647].
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check 4-Aminophenol in the storage compatibility matrix →