Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

2-Methoxyethanol

2-Methoxyethanol is a colorless liquid with a mild agreeable odor.

CAS 109-86-4 C3H8O2 76.09 g/mol Danger

01 · Identification

What 2-Methoxyethanol is

2-Methoxyethanol is a colorless liquid with a mild agreeable odor. Its molecular formula is C3H8O2 and its molecular weight is 76.09 g/mol. It boils at 124 °C, melts at -85.1 °C, is miscible with water.

Under the GHS it carries the signal word Danger. It is classed as teratogens.

CAS number109-86-4
EC number203-713-7
Index number603-011-00-4
Molecular formulaC3H8O2
Molecular weight76.09 g/mol
Chemical class Teratogens

Other names for 2-Methoxyethanol

  • ethylene glycol monomethyl ether

02 · GHS classification

Hazards and label elements

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Signal wordDanger
Hazard statements assigned to 2-Methoxyethanol
CodeHazard statement
H226 Flammable liquid and vapour.
H360FD May damage fertility. May damage the unborn child.
H332 Harmful if inhaled.
H312 Harmful in contact with skin.
H302 Harmful if swallowed.

Precautionary statements: P210, P233, P241, P242, P260, P270, P271, P280, P301, P302, P304, P312, P330, P352, P403

03 · Physical and chemical properties

2-Methoxyethanol properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Property Value Conditions Source
Boiling point 124.1 °C (255.4 °F) HSDB
124.44 °C (256 °F) NIOSH
125 °C (257 °F) at 768 mmHg CAMEO
Melting point -85.1 °C (-121.2 °F) HSDB
-85 °C (-121 °F) NIOSH
-85.11 °C (-121.2 °F) CAMEO
Density 0.9586 g/cm³ HSDB
0.96 g/cm³ NIOSH
0.9647 g/cm³ at 20 °C HSDB
Solubility Miscible with water HSDB
Miscible with alcohol, ether, acetone, dimethylformamide HSDB
Miscible with hydrocarbons, alcohols, ketones, glycols HSDB
Vapor pressure 6 mmHg NIOSH
6.2 mmHg at 20 °C CAMEO
9.5 mmHg at 25 °C HSDB
Flash point 42 °C (107.6 °F) HSDB
120 °C (248 °F) HSDB
40 °C (104 °F) HSDB
Autoignition temperature 285 °C (545 °F) HSDB
288.33 °C (551 °F) CAMEO
Lower explosive limit (LEL) 1.8 % by volume HSDB
2.5 % by volume HSDB
Upper explosive limit (UEL) 24.5 % by volume HSDB
19.8 % by volume HSDB
14 % by volume NIOSH
Vapor density 2.62 (air = 1) HSDB
2.6 (air = 1) ICSC
Odor threshold Detection: 9X10-2 ppm (air); Recognition: 2.2X10-1 ppm (air) HSDB
Odor Threshold Low: 0.09 [ppm] Haz-Map
Critical temperature and pressure 324.45 °C (616 °F) HSDB
Corrosivity Methyl cellosolve will attack some forms of plastics, rubber, and coatings. HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

04 · Source notes

Further notes on 2-Methoxyethanol

These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.

Odor

Under controlled conditions and using human volunteers ...the odor threshold for ethylene glycol monomethyl ether was approx 60 ppm and the level of strong odor 90 ppm. In another study, human volunteers were exposed to levels of 25 and 115 ppm for a full working day. The 25-ppm level was considered to be the max tolerated odor level by three of five people, whereas the intolerable level appeared to be more than 115 ppm.

Source: HSDB

05 · Handling and storage

Storing and handling 2-Methoxyethanol

Storage conditions

Fireproof. Separated from strong oxidants and food and feedstuffs. Keep in the dark. Cool.

Source: Hazardous Substances Data Bank (HSDB)

Incompatible materials

Ethylene glycol monomethyl ether /in air/ forms peroxides that are highly explosive.

Source: Hazardous Substances Data Bank (HSDB)

Reactivity

ETHYLENE GLYCOL MONOMETHYL ETHER is incompatible with oxygen and strong oxidizing agents. Contact with bases may result in decomposition. Incompatible with acid chlorides and acid anhydrides. (NTP, 1992). It forms explosive peroxides.

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check 2-Methoxyethanol in the storage compatibility matrix →

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