Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

2-Butyne-1,4-diol

2-Butyne-1,4-diol is plates from benzene and ethyl acetate.

CAS 110-65-6 C4H6O2 86.09 g/mol Danger

01 · Identification

What 2-Butyne-1,4-diol is

2-Butyne-1,4-diol is plates from benzene and ethyl acetate. Its molecular formula is C4H6O2 and its molecular weight is 86.09 g/mol. It boils at 238 °C, melts at 50 °C, is soluble in water.

Under the GHS it carries the signal word Danger. It is classed as reactive agents - 1st degree.

CAS number110-65-6
EC number203-788-6
Index number603-076-00-9
Molecular formulaC4H6O2
Molecular weight86.09 g/mol
Chemical class Reactive agents - 1st degree

Other names for 2-Butyne-1,4-diol

  • but-2-yne-1,4-diol

02 · GHS classification

Hazards and label elements

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Signal wordDanger
Hazard statements assigned to 2-Butyne-1,4-diol
CodeHazard statement
H331 Toxic if inhaled.
H301 Toxic if swallowed.
H312 Harmful in contact with skin.
H373 May cause damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
H314 Causes severe skin burns and eye damage.
H317 May cause an allergic skin reaction.

Precautionary statements: P260, P261, P270, P271, P272, P280, P301, P302, P304, P310, P312, P313, P314, P330, P331, P333, P352

03 · Physical and chemical properties

2-Butyne-1,4-diol properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Property Value Conditions Source
Boiling point 238 °C (460.4 °F) HSDB
237.78 °C (460 °F) at 760 mmHg CAMEO
238 °C (460.4 °F) at 760 mmHg DOE PAC
Melting point 50 °C (122 °F) HSDB
58 °C (136.4 °F) ICSC
Density 1.1 g/cm³ ICSC
1.115 g/cm³ at 20 °C HSDB
1.07 g/cm³ at 20 °C CAMEO
Solubility Insoluble in benzene; slightly soluble in ethyl ether, choroform; very soluble in ethanol, acetone, methanol HSDB
Soluble in aqueous acids. HSDB
In water, 3.74X10+6 mg/L at 25 °C at 25 °C HSDB
Vapor pressure 0.0015 mmHg at 20 °C ICSC
0.000556 mmHg at 25 °C HSDB
0.000556 mmHg Haz-Map
Flash point 128.33 °C (263 °F) HSDB
152 °C (305.6 °F) ICSC
Autoignition temperature 335 °C (635 °F) ICSC
Lower explosive limit (LEL) Explosive reaction with traces of alkalies, alkali earth hydroxides, halide salts, strong acids, mercury salts plus strong acids. HSDB
Vapor density 3 (air = 1) ICSC

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

04 · Handling and storage

Storing and handling 2-Butyne-1,4-diol

Storage conditions

The storage temperature should be kept below 40 °C and storage times longer than a few months should be avoided because the butynediol flakes tend to set up.

Source: Hazardous Substances Data Bank (HSDB)

Incompatible materials

The pure diol may be distilled unchanged, but traces of alkali or alkaline earth hydroxides or halides may cause explosive decomposition during distillation. In presence of strong acids, mercury salts may cause violent decomposition of the diol.

Source: Hazardous Substances Data Bank (HSDB)

Reactivity

Pure 1,4-BUTYNEDIOL is non-explosive. Small amounts of certain impurities-alkali hydroxides, alkaline earth hydroxides, halides-may cause explosive decomposition upon distillation. Butynediol should not be treated with basic catalysts in the absence of a solvent at room temperature, and its stability is less with elevated temperatures. In strong acids, contamination with mercury salts can also result in violent decomposition. [NFPA 491M 1991].

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check 2-Butyne-1,4-diol in the storage compatibility matrix →

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