Substance profile
2-Aminophenol
2-Aminophenol is crystals, rapidly becoming brown.
01 · Identification
What 2-Aminophenol is
2-Aminophenol is crystals, rapidly becoming brown. It boils at 243 °C, melts at 174 °C.
Under the GHS it carries the signal word Warning.
02 · GHS classification
Hazards and label elements
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
| Code | Hazard statement |
|---|---|
| H341 | Suspected of causing genetic defects <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H332 | Harmful if inhaled. |
| H302 | Harmful if swallowed. |
Precautionary statements: P201, P260, P270, P271, P280, P301, P304, P308, P312, P313, P330
03 · Physical and chemical properties
2-Aminophenol properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 243 °C (469.4 °F) | at 760 mmHg | DOE PAC |
| 153 °C (307.4 °F) | sublimes | HSDB | |
| 152.78 °C (307 °F) | sublimes, at 11 mmHg (reduced pressure) | CAMEO | |
| Melting point | 174 °C (345.2 °F) | DOE PAC | |
| 172 °C (341.6 °F) | range, midpoint shown | HSDB | |
| 172.5 °C (342.5 °F) | range, midpoint shown | HSDB | |
| Density | 1.328 g/cm³ | CAMEO | |
| 1.3 g/cm³ | ICSC | ||
| 1.328 g/cm³ | at 25 °C | HSDB | |
| Solubility | 1 g dissolves in 50 mL cold water, 23 mL alcohol | HSDB | |
| Soluble in ethyl ether; very soluble in ethanol; slightly soluble in benzene, trifluoroacetic acid | HSDB | ||
| Vapor pressure | 0.0005 mmHg | Haz-Map | |
| negligible | ICSC | ||
| Flash point | 168 °C (334.4 °F) | HSDB | |
| 175 °C (347 °F) | above this value | ICSC | |
| Autoignition temperature | 190 °C (374 °F) | HSDB | |
| Vapor density | 3.77 (air = 1) | ICSC |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
04 · Source notes
Further notes on 2-Aminophenol
These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.
Solubility
Slightly soluble in toluene, chloroform, and cold water; soluble in ethanol, and hot water, very soluble in acetonitrile, ethyl acetate, acetone, dimethyl sulfoxide
Source: HSDB
05 · Handling and storage
Storing and handling 2-Aminophenol
Storage conditions
Store in tightly closed containers in a cool, well-ventilated area. Aminophenols must be stored to avoid contact with strong oxidizers (such as chlorine, bromine, and fluorine), since violent reactions occur. /Aminophenols/
Source: Hazardous Substances Data Bank (HSDB)
Incompatible materials
Incompatible with acids, acid chlorides, and anhydrides, chloroformates, strong oxidizing agents.
Source: Hazardous Substances Data Bank (HSDB)
Reactivity
O-AMINOPHENOL can react with oxidizing agents. (NTP, 1992) THF forms explosive products with 2-aminophenol [Lewis 3227].
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check 2-Aminophenol in the storage compatibility matrix →