Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

Musk ketone

Musk ketone is yellow crystals with a sweet, very persistent, slightly animal musk odor.

CAS 81-14-1 C14H18N2O5 294.3 g/mol Warning

01 · Identification

What Musk ketone is

Musk ketone is yellow crystals with a sweet, very persistent, slightly animal musk odor. Its molecular formula is C14H18N2O5 and its molecular weight is 294.3 g/mol. It melts at 136 °C.

Under the GHS it carries the signal word Warning.

CAS number81-14-1
EC number201-328-9
Index number609-069-00-7
Molecular formulaC14H18N2O5
Molecular weight294.3 g/mol

Other names for Musk ketone

  • 3,5-dinitro-2,6-dimethyl-4-tert-butylacetophenone
  • 4'-tert-butyl-2',6'-dimethyl-3',5'-dinitroacetophenone

02 · GHS classification

Hazards and label elements

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Signal wordWarning
Hazard statements assigned to Musk ketone
CodeHazard statement
H351 Suspected of causing cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
H400 Very toxic to aquatic life.
H410 Very toxic to aquatic life with long lasting effects.

Precautionary statements: P201, P273, P280, P308, P313, P391, P501

This page lists only the codes assigned to Musk ketone. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

03 · Physical and chemical properties

Musk ketone properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Property Value Conditions Source
Melting point 135.5 °C (275.9 °F) HSDB
135.5 °C (275.9 °F) range, midpoint shown CAMEO
135.75 °C (276.4 °F) range, midpoint shown HMDB
Density 0.73 g/cm³ HSDB
Solubility Very soluble in chloroform HSDB
Insoluble (<1 mg/ml at 68.0 °F) (NTP, 1992) at 20 °C CAMEO
In water, 0.46 mg/L at 25 °C at 25 °C HSDB
Vapor pressure 3e-7 mmHg at 25 °C HSDB
Flash point 168 °C (334.4 °F) above this value HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

04 · Handling and storage

Storing and handling Musk ketone

Storage conditions

Keep container tightly closed in a dry and well-ventilated place.

Source: Hazardous Substances Data Bank (HSDB)

Incompatible materials

Incompatible materials: Strong acids, strong bases.

Source: Hazardous Substances Data Bank (HSDB)

Reactivity

A nitrated ketone. Ketones are reactive with many acids and bases liberating heat and flammable gases (e.g., H2). The amount of heat may be sufficient to start a fire in the unreacted portion of the ketone. Ketones react with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable gas (H2) and heat. Ketones are incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides. They react violently with aldehydes, HNO3, HNO3 + H2O2, and HClO4.

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check Musk ketone in the storage compatibility matrix →

Safety Data Sheet

Getting an SDS for Musk ketone

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Musk ketone issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

Nearby

Substances next to Musk ketone

Keep going: substances starting with M, or search the whole database by name, CAS number, pictogram or signal word.

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