Substance profile
Dimethylacetamide
Dimethylacetamide is a liquid with an AMINE odor.
01 · Identification
What Dimethylacetamide is
Dimethylacetamide is a liquid with an AMINE odor. Its molecular formula is C4H9NO and its molecular weight is 87.12 g/mol. It boils at 165 °C, melts at -18.6 °C, is soluble in water.
Under the GHS it carries the signal word Danger. It is classed as flammable agents - 2nd degree.
Other names for Dimethylacetamide
- N,N-dimethylacetamide
02 · GHS classification
Hazards and label elements
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
| Code | Hazard statement |
|---|---|
| H360D | May damage the unborn child. |
| H332 | Harmful if inhaled. |
| H312 | Harmful in contact with skin. |
Precautionary statements: P260, P271, P280, P302, P304, P312, P352
03 · Physical and chemical properties
Dimethylacetamide properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 165 °C (329 °F) | NIOSH | |
| 166.11 °C (331 °F) | at 760 mmHg | CAMEO | |
| Melting point | -18.59 °C (-1.5 °F) | HSDB | |
| -20 °C (-4 °F) | NIOSH | ||
| Density | 0.94 g/cm³ | NIOSH | |
| 0.943 g/cm³ | at 20 °C | CAMEO | |
| 0.9366 g/cm³ | at 25 °C | HSDB | |
| Solubility | SOL IN BENZENE | HSDB | |
| Soluble in alcohol, acetone, ether | HSDB | ||
| Miscible with most org solvents | HSDB | ||
| Vapor pressure | 2 mmHg | NIOSH | |
| 2.4752 mmHg | at 20 °C | ICSC | |
| 2 mmHg | at 25 °C | HSDB | |
| Flash point | 70 °C (158 °F) | OPEN CUP | HSDB |
| 70 °C (158 °F) | NIOSH | ||
| 66.11 °C (151 °F) | CAMEO | ||
| Autoignition temperature | 490 °C (914 °F) | HSDB | |
| Lower explosive limit (LEL) | 1.8 % by volume | CAMEO | |
| Upper explosive limit (UEL) | 13.8 % by volume | CAMEO | |
| 11.5 % by volume | ICSC | ||
| 11.5 % by volume | at 100 °C | HSDB | |
| Vapor density | 3.01 (air = 1) | HSDB | |
| Odor threshold | ODOR THRESHOLD FOR 50% RESPONSE IS 21.4 PPM; FOR 100% RESPONSE, 46.8 PPM. | HSDB | |
| Odor low: 163.8 mg/cu m; Odor high: 163.8 mg/cu m | HSDB | ||
| Odor Threshold Low: 21.0 [ppm] | Haz-Map | ||
| Critical temperature and pressure | 385 °C (725 °F) | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
04 · Handling and storage
Storing and handling Dimethylacetamide
Storage conditions
MATERIALS WHICH ARE TOXIC AS STORED OR WHICH CAN DECOMPOSE INTO TOXIC COMPONENTS ... SHOULD BE STORED IN A COOL WELL VENTILATED PLACE, OUT OF DIRECT RAYS OF THE SUN, AWAY FROM AREAS OF HIGH FIRE HAZARD, AND SHOULD BE PERIODICALLY INSPECTED. INCOMPATIBLE MATERIALS SHOULD BE ISOLATED ... .
Source: Hazardous Substances Data Bank (HSDB)
Incompatible materials
Carbon tetrachloride, other halogenated compounds when in contact with iron, oxidizers.
Source: Hazardous Substances Data Bank (HSDB)
Reactivity
DIMETHYLACETAMIDE is an amide. Incompatible with oxidizing agents and halogenated compounds. Exothermic reactions occur with carbon tetrachloride and hexachlorocyclohexane. It can react violently in the presence of iron. (NTP, 1992) Special Hazards of Combustion Products: Emits carbon oxides, nitrogen oxides, and dimethylamine when heated to decomposition.
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check Dimethylacetamide in the storage compatibility matrix →