Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

Build a label

Substance profile

Clothianidin

Clothianidin is a colorless powder and is odorless.

CAS 210880-92-5 C6H8ClN5O2S 249.68 g/mol Danger

01 · Identification

What Clothianidin is

Clothianidin is a colorless powder and is odorless. Its molecular formula is C6H8ClN5O2S and its molecular weight is 249.68 g/mol. It melts at 177 °C.

Under the GHS it carries the signal word Danger.

CAS number210880-92-5
EC number433-460-1
Index number613-307-00-5
Molecular formulaC6H8ClN5O2S
Molecular weight249.68 g/mol

Other names for Clothianidin

  • clothianidin (ISO)
  • (E)-1-(2-chloro–1,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidine

02 · GHS classification

Hazards and label elements

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Signal wordDanger
Hazard statements assigned to Clothianidin
CodeHazard statement
H361f Suspected of damaging fertility.
H302 Harmful if swallowed.
H370 Causes damage to organs <or state all organs affected, if known> <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
H400 Very toxic to aquatic life.
H410 Very toxic to aquatic life with long lasting effects.

Precautionary statements: P260, P270, P273, P301, P308, P311, P312, P330, P391, P501

03 · Physical and chemical properties

Clothianidin properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Property Value Conditions Source
Melting point 176.8 °C (350.2 °F) HSDB
Density 1.2632 g/cm³ End-use HSDB
1.61 g/cm³ at 20 °C HSDB
Solubility In water, 0.304 (pH 4), 0.340 (pH 10) (both g/L, 20 °C) at 20 °C HSDB
In water, 327 mg/L at 20 °C at 20 °C HSDB
In heptane less than 0.00104, xylene 0.0128, dichloromethane 1.32, methanol 6.26, octanol 0.938, acetone 15.2, ethyl acetate 2.03 (all in g/L, 25 °C) at 25 °C HSDB
Vapor pressure 0.0009751 mmHg at 25 °C HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

04 · Handling and storage

Storing and handling Clothianidin

Storage conditions

Keep container tightly closed in a dry and well-ventilated place. Storage class (TRGS 510): 13: Non Combustible Solids.

Source: Hazardous Substances Data Bank (HSDB)

Incompatible materials

Incompatible materials: Strong oxidizing agents.

Source: Hazardous Substances Data Bank (HSDB)

Planning storage for a mix of chemicals? Check Clothianidin in the storage compatibility matrix →

Get the free GHS / CLP / OSHA deadline calendar

Verified 2026–2029 compliance dates in one PDF — plus alerts when the rules change.