Substance profile
Bronopol
Bronopol is a white crystalline powder and is odorless.
01 · Identification
What Bronopol is
Bronopol is a white crystalline powder and is odorless. Its molecular formula is C3H6BrNO4 and its molecular weight is 199.99 g/mol. It boils at 152 °C, melts at 132 °C.
Under the GHS it carries the signal word Danger.
Other names for Bronopol
- bronopol (INN)
- 2-bromo-2-nitropropane-1,3-diol
02 · GHS classification
Hazards and label elements
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
| Code | Hazard statement |
|---|---|
| H312 | Harmful in contact with skin. |
| H302 | Harmful if swallowed. |
| H335 | May cause respiratory irritation. |
| H315 | Causes skin irritation. |
| H318 | Causes serious eye damage. |
| H400 | Very toxic to aquatic life. |
Precautionary statements: P264, P270, P273, P280, P301, P302, P305, P310, P312, P313, P330, P332, P338, P352, P391, P501
03 · Physical and chemical properties
Bronopol properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 151.72 °C (305.1 °F) | at 760 mmHg | CAMEO |
| 130 °C (266 °F) | DrugBank | ||
| Melting point | 131.5 °C (268.7 °F) | HSDB | |
| 131.39 °C (268.5 °F) | range, midpoint shown | CAMEO | |
| 121 °C (249.8 °F) | range, midpoint shown | ICSC | |
| Density | 1.9 g/cm³ | ICSC | |
| Solubility | In water, 2.5X10+5 mg/L at 22 °C | at 22 °C | HSDB |
| Soluble in alcohol, ethyl acetate. Slightly soluble in chloroform, acetone, ether, benzene. Insoluble in ligroin. | HSDB | ||
| Solubility in water, g/100ml at 23 °C: 28 (freely soluble) | at 23 °C | ICSC | |
| Vapor pressure | 0.0000126 mmHg | at 20 °C | HSDB |
| Vapor pressure, Pa at 20 °C: | at 20 °C | ICSC | |
| Flash point | 167 °C (332.6 °F) | ICSC |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
04 · Handling and storage
Storing and handling Bronopol
Storage conditions
Keep container tightly closed in a dry well-ventilated place.
Source: Hazardous Substances Data Bank (HSDB)
Incompatible materials
An aqueous solution of bronopol degrades in the presence of cupric and ferric ions as well as aluminum and tin metals.
Source: Hazardous Substances Data Bank (HSDB)
Reactivity
Incompatible with strong oxidizing agents, strong bases, strong reducing agents, acid chlorides and acid anhydrides. It is also incompatible with sulfhydryl compounds or with aluminum or iron containers (it is stable in contact with tin or stainless steel). (NTP, 1992)
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check Bronopol in the storage compatibility matrix →