Substance profile
Amitrole
Amitrole is a transparent to off white crystalline powder and is odorless.
01 · Identification
What Amitrole is
Amitrole is a transparent to off white crystalline powder and is odorless. Its molecular formula is C2H4N4 and its molecular weight is 84.08 g/mol. It melts at 159 °C.
Under the GHS it carries the signal word Warning. It is classed as carcinogens.
Other names for Amitrole
- amitrole (ISO)
- 1,2,4-triazol-3-ylamine
02 · GHS classification
Hazards and label elements
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
| Code | Hazard statement |
|---|---|
| H361d | Suspected of damaging the unborn child. |
| H373 | May cause damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H411 | Toxic to aquatic life with long lasting effects. |
Precautionary statements: P260, P270, P273, P314, P391, P501
03 · Physical and chemical properties
Amitrole properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 159 °C (318.2 °F) | HSDB | |
| 158.89 °C (318 °F) | NIOSH | ||
| Density | 1.14 g/cm³ | NIOSH | |
| 1.138 g/cm³ | at 20 °C | HSDB | |
| Solubility | In water, 2.8X10+5 mg/L at 25 °C | at 25 °C | HSDB |
| (77 °F): 28% | at 25 °C | NIOSH | |
| Solubility in water, g/l at 25 °C: 280 | at 25 °C | ICSC | |
| Vapor pressure | 4.41e-7 mmHg | at 20 °C | CAMEO |
| 0.000001 mmHg | at 20 °C | DOE PAC | |
| 4.4e-7 mmHg | at 25 °C | HSDB | |
| Lower explosive limit (LEL) | Noncombustible Solid, but may be dissolved in flammable liquids. | NIOSH | |
| Vapor density | 2.9 (air = 1) | ICSC | |
| Corrosivity | MILDLY CORROSIVE TO IRON, ALUMINUM, COPPER, & COPPER ALLOYS. | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
04 · Handling and storage
Storing and handling Amitrole
Storage conditions
Store at room temperature
Source: Hazardous Substances Data Bank (HSDB)
Incompatible materials
Light (decomposes), strong oxidizers [Note: Corrosive to iron, aluminum & copper].
Source: Hazardous Substances Data Bank (HSDB)
Reactivity
AMITROLE is a triazole derivative. The triazoles are a group that contain several derivatives that are highly explosive materials. They are sensitive to heat, friction, and impact. Sensitivity varies with the type substitution to the triazole ring. Metal chelated and halogen substitution of the triazole ring make for a particularly heat sensitive material. Azido and nitro derivatives have been employed as high explosives. No matter the derivative these materials should be treated as explosives. AMITROLE forms chelates with some metals. It is corrosive to iron, copper and aluminum. Forms salts with most acids and alkalis. This compound is incompatible with strong oxidizers, strong acids, acid chlorides and acid anhydrides (NTP, 1992).
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check Amitrole in the storage compatibility matrix →