Substance profile
2-Nitroanisole
2-Nitroanisole is a colorless to yellowish liquid.
01 · Identification
What 2-Nitroanisole is
2-Nitroanisole is a colorless to yellowish liquid. Its molecular formula is C7H7NO3 and its molecular weight is 153.14 g/mol. It boils at 277 °C, melts at 10.5 °C.
Under the GHS it carries the signal word Danger. It is classed as carcinogens.
02 · GHS classification
Hazards and label elements
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
| Code | Hazard statement |
|---|---|
| H350 | May cause cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H302 | Harmful if swallowed. |
Precautionary statements: P201, P270, P280, P301, P308, P312, P313, P330
03 · Physical and chemical properties
2-Nitroanisole properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 277 °C (530.6 °F) | ICSC | |
| 269.5 °C (517.1 °F) | range, midpoint shown | HSDB | |
| 277 °C (530.6 °F) | at 4 mmHg (reduced pressure) | HSDB | |
| Melting point | 10.5 °C (50.9 °F) | HSDB | |
| Density | 1.254 g/cm³ | at 20 °C | HSDB |
| 1.25 g/cm³ | at 20 °C | ICSC | |
| Solubility | Miscible with ethanol, ethyl ether; soluble in carbon tetrachloride | HSDB | |
| In water, 1.69X10+3 mg/L at 30 °C | at 30 °C | HSDB | |
| Solubility in water, g/l at 30 °C: 1.69 (slightly soluble) | at 30 °C | ICSC | |
| Vapor pressure | 0.0036 mmHg | at 25 °C | HSDB |
| 0.03 mmHg | at 30 °C | ICSC | |
| 0.0036 mmHg | Haz-Map | ||
| Flash point | 142 °C (287.6 °F) | HSDB | |
| 124 °C (255.2 °F) | Haz-Map | ||
| Autoignition temperature | 464 °C (867.2 °F) | HSDB | |
| Lower explosive limit (LEL) | 1.04 % by volume | at 150 °C | ICSC |
| The explosion of 400 g of o-nitroanisole during reduction using nickel as a catalyst has been reported. | HSDB | ||
| Catalytic hydrogenation of nitroanisole in the presence of nickel catalyst has resulted in an explosion. | HSDB | ||
| Upper explosive limit (UEL) | 66 % by volume | at 150 °C | ICSC |
| Vapor density | 5.29 (air = 1) | ICSC |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
04 · Handling and storage
Storing and handling 2-Nitroanisole
Storage conditions
Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Source: Hazardous Substances Data Bank (HSDB)
Planning storage for a mix of chemicals? Check 2-Nitroanisole in the storage compatibility matrix →