Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

Ethyl acetate

Ethyl acetate is a clear, volatile with a characteristic ether-like odor reminiscent of pineapple.

CAS 141-78-6 Danger

Ethyl acetate Safety Data Sheet →

01 · Identification

What Ethyl acetate is

Ethyl acetate is a clear, volatile with a characteristic ether-like odor reminiscent of pineapple. It boils at 77.1 °C, melts at -83.8 °C.

Under the GHS it carries the signal word Danger. It is classed as flammable agents - 3rd degree.

CAS number141-78-6
EC number205-500-4
Index number607-022-00-5
Chemical class Flammable agents - 3rd degree

Other names for Ethyl acetate

  • EtOAc
  • acetic ester
  • Acetic Acid, Ethyl Ester
  • Acetic Ether
  • Acetidin
  • Acetoxyethane
  • Ethyl Acetic Ester
  • Ethyl Ester Of Acetic Acid
  • Ethyl Ethanoate
  • Vinegar Naphtha

02 · GHS classification

Hazards and label elements

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Signal wordDanger
Hazard statements assigned to Ethyl acetate
CodeHazard statement
H225 Highly flammable liquid and vapour.
H336 May cause drowsiness or dizziness.
H319 Causes serious eye irritation.

Supplemental EU statements: EUH066

Precautionary statements: P210, P233, P241, P242, P264, P280, P305, P313, P337, P338, P403

03 · Physical and chemical properties

Ethyl acetate properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Property Value Conditions Source
Boiling point 77.1 °C (170.8 °F) HSDB
77.22 °C (171 °F) NIOSH
77.22 °C (171 °F) at 760 mmHg CAMEO
Melting point -83.8 °C (-118.8 °F) HSDB
-82.78 °C (-117 °F) NIOSH
-83.61 °C (-118.5 °F) CAMEO
Density 0.9 g/cm³ NIOSH
0.9003 g/cm³ at 20 °C HSDB
0.902 g/cm³ at 20 °C CAMEO
Solubility Miscible with ethanol, ethyl ether; very soluble in acetone, benzene HSDB
In water, 8.0X10+4 mg/L at 25 °C at 25 °C HSDB
Very soluble in water (64 g/L at 25 °C) at 25 °C HSDB
Vapor pressure 73 mmHg NIOSH
73 mmHg at 20 °C CAMEO
93.2 mmHg at 25 °C HSDB
Flash point -4.44 °C (24 °F) NIOSH
-4 °C (24.8 °F) ICSC
Autoignition temperature 426.67 °C (800 °F) CAMEO
427 °C (800.6 °F) ICSC
Lower explosive limit (LEL) 2.2 % by volume HSDB
0.025 % by volume HSDB
2 % by volume NIOSH
Upper explosive limit (UEL) 11.5 % by volume HSDB
0.09 % by volume HSDB
Vapor density 3.04 (air = 1) HSDB
3 (air = 1) ICSC
Odor threshold Ethyl acetate has a fruity odor and an odor threshold of 3.9 ppm. HSDB
Detection in air: 3.6-1.120 mg cu/m HSDB
0.0196 mg/cu m (low odor); 665.0 mg/cu m (high odor); 350 mg/cu m (irritating concn) HSDB
Critical temperature and pressure 250.55 °C (483 °F) HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

04 · Handling and storage

Storing and handling Ethyl acetate

Storage conditions

Keep tightly closed in cool place.

Source: Hazardous Substances Data Bank (HSDB)

Incompatible materials

... can react vigorously with oxidizing materials ... Potentially explosive reaction with lithium tetrahydroaluminate. Ignites on contact with potassium teri-butoxide. Violent reaction with chlorosulfonic acid, (LiAIH2 + 2-chloromethyl furan), oleum.

Source: Hazardous Substances Data Bank (HSDB)

Reactivity

ETHYL ACETATE is also sensitive to heat. On prolonged storage, materials containing similar functional groups have formed explosive peroxides. This chemical may ignite or explode with lithium aluminum hydride. It may also ignite with potassium tert-butoxide. It is incompatible with nitrates, strong alkalis and strong acids. It will attack some forms of plastics, rubber and coatings. It is incompatible with oxidizers such as hydrogen peroxide, nitric acid, perchloric acid and chromium trioxide. Violent reactions occur with chlorosulfonic acid. (NTP, 1992). SOCl2 reacts with esters, such as ethyl acetate, forming toxic SO2 gas and water soluble/toxic acyl chlorides, catalyzed by Fe or Zn (Spagnuolo, C.J. et al. 1992. Chemical and Engineering News 70(22):2.).

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check Ethyl acetate in the storage compatibility matrix →

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