Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

Diethyl ether

Diethyl ether is colorless, volatile, mobile liquid with a sweetish, pungent odor.

CAS 60-29-7 C4H10O 74.12 g/mol Danger

Diethyl ether Safety Data Sheet →

01 · Identification

What Diethyl ether is

Diethyl ether is colorless, volatile, mobile liquid with a sweetish, pungent odor. Its molecular formula is C4H10O and its molecular weight is 74.12 g/mol. It boils at 34.6 °C, melts at -116 °C.

Under the GHS it carries the signal word Danger. It is classed as flammable agents - 4th degree.

CAS number60-29-7
EC number200-467-2
Index number603-022-00-4
Molecular formulaC4H10O
Molecular weight74.12 g/mol
Chemical class Flammable agents - 4th degree

Other names for Diethyl ether

  • ether
  • ethyl ether
  • Aether
  • Anaesthetic Ether
  • Anesthesia Ether
  • Anesthetic Ether
  • Diethyl Ether (Ethyl Ether)
  • Diethyl Oxide
  • Ethane, 1,1'-Oxybis-
  • Ethoxyethane
  • Ethyl Oxide
  • 3-Oxapentane
  • 1,1'-Oxybisethane
  • Pronarcol

02 · GHS classification

Hazards and label elements

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Signal wordDanger
Hazard statements assigned to Diethyl ether
CodeHazard statement
H224 Extremely flammable liquid and vapour.
H302 Harmful if swallowed.
H336 May cause drowsiness or dizziness.

Supplemental EU statements: EUH019, EUH066

Precautionary statements: P210, P233, P241, P242, P270, P301, P312, P330, P403

03 · Physical and chemical properties

Diethyl ether properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Property Value Conditions Source
Boiling point 34.6 °C (94.3 °F) at 760 mmHg HSDB
34.44 °C (94 °F) NIOSH
34.61 °C (94.3 °F) at 760 mmHg CAMEO
Melting point -116.3 °C (-177.3 °F) stable crystals HSDB
-116.11 °C (-177 °F) NIOSH
-116.28 °C (-177.3 °F) CAMEO
Density 0.71 g/cm³ NIOSH
0.7134 g/cm³ at 20 °C HSDB
0.714 g/cm³ at 20 °C CAMEO
Solubility Miscible with lower aliphatic alcohols, benzene, chloroform, petroleum ether, fat solvents, many oils; sol in concn hydrochloric acid HSDB
Sol in acetone; very sol in ethanol HSDB
Sol in solvent naphtha, benzene, oils HSDB
Vapor pressure 440 mmHg NIOSH
442 mmHg at 20 °C CAMEO
538 mmHg at 25 °C HSDB
Flash point -45 °C (-49 °F) CLOSED CUP HSDB
-45 °C (-49 °F) NIOSH
Autoignition temperature 180 °C (356 °F) HSDB
170 °C (338 °F) range, midpoint shown ICSC
Lower explosive limit (LEL) 1.9 % by volume HSDB
36.5 % by volume HSDB
Upper explosive limit (UEL) 36 % by volume HSDB
Vapor density 2.55 (air = 1) Air = 1.0 HSDB
2.6 (air = 1) CAMEO
Odor threshold 0.83 ppm (purity not given) HSDB
Odor detection: in water= 5.83 ppm; in air= 5.83 mg/l (gas); in air: 7.00x10(-1) ppm Purities not specified HSDB
0.99 mg/cu m (odor low) 3.0 mg/cu m (odor high) HSDB
Critical temperature and pressure 192.7 °C (378.9 °F) HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

04 · Handling and storage

Storing and handling Diethyl ether

Storage conditions

Separate from oxidizing materials. Store in a cool, dry, well-ventilated area. Avoid sunlight.

Source: Hazardous Substances Data Bank (HSDB)

Incompatible materials

Boron triazide, bromine trifluoride, bromine pentafluoride, bromine, iodine heptafluoride, silver perchlorate, fluorine nitrate, permanganic acid, nitric acid, hydrogen peroxide, peroxodisulfuric acid, iodine(VII) oxide, peat soils, thiotriazyl perchlorate, sulfonyl chloride, sulfur, uranyl nitrate, and wood pulp extracts.

Source: Hazardous Substances Data Bank (HSDB)

Reactivity

Occasional explosions have occurred when aluminum hydride was stored in ether. The explosions have been blamed on the presence of carbon dioxide impurity in the ether, [J. Amer. Chem. Soc. 70:877(1948)]. Diethyl ether and chromium trioxide react violently at room temperature. Solid acetyl peroxide in contact with ether or any volatile solvent may explode violently. A 5-gram portion in ether detonated while being carried, [Chem. Eng. News 27:175(1949)]. Nitrosyl perchlorate ignites and explodes with diethyl ether. A mixture of ether and ozone forms aldehyde and acetic acid and a heavy liquid, ethyl peroxide, an explosive, [Mellor 1:911(1946-1947)].

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check Diethyl ether in the storage compatibility matrix →

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