Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

3-Methyl-2-butanone

3-Methyl-2-butanone is a colorless liquid with the odor threshold lies between 1.9 and 3.1 ppm (6.8 and 11 mg/cu m).

CAS 563-80-4 C5H10O 86.13 g/mol Danger

01 · Identification

What 3-Methyl-2-butanone is

3-Methyl-2-butanone is a colorless liquid with the odor threshold lies between 1.9 and 3.1 ppm (6.8 and 11 mg/cu m). Its molecular formula is C5H10O and its molecular weight is 86.13 g/mol. It boils at 94.3 °C, melts at -93.1 °C.

Under the GHS it carries the signal word Danger. It is classed as flammable agents - 3rd degree.

CAS number563-80-4
EC number209-264-3
Index number606-007-00-0
Molecular formulaC5H10O
Molecular weight86.13 g/mol
Chemical class Flammable agents - 3rd degree

Other names for 3-Methyl-2-butanone

  • 3-methylbutan-2-one
  • methyl isopropyl ketone

02 · GHS classification

Hazards and label elements

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Signal wordDanger
Hazard statements assigned to 3-Methyl-2-butanone
CodeHazard statement
H225 Highly flammable liquid and vapour.

Precautionary statements: P210, P233, P241, P242, P403

03 · Physical and chemical properties

3-Methyl-2-butanone properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Property Value Conditions Source
Boiling point 94.33 °C (201.8 °F) HSDB
92.78 °C (199 °F) NIOSH
93.89 °C (201 °F) at 760 mmHg CAMEO
Melting point -93.1 °C (-135.6 °F) HSDB
-92.22 °C (-134 °F) NIOSH
Density 0.81 g/cm³ NIOSH
0.8501 g/cm³ at 20 °C HSDB
0.8051 g/cm³ at 20 °C CAMEO
Solubility Miscible with ethanol, ethyl ether; very soluble in acetone; soluble in carbon tetrachloride HSDB
Very slight NIOSH
In water, 5.237X10+4 mg/L at 20 °C at 20 °C HSDB
Vapor pressure 42 mmHg NIOSH
67.21 mmHg CAMEO
52.5 mmHg at 25 °C, extrapolated HSDB
Flash point 11.11 °C (52 °F) HSDB
6.11 °C (43 °F) CAMEO
-1 °C (30.2 °F) ICSC
Autoignition temperature -16.78 °C (1.8 °F) HSDB
475 °C (887 °F) ICSC
Lower explosive limit (LEL) 1.2 % by volume ICSC
Lower limit 9.0 °F; Upper limit 0.85 °F HSDB
Combustible Liquid NIOSH
Upper explosive limit (UEL) 8 % by volume ICSC
Vapor density 3 (air = 1) ICSC
Odor threshold Odor Threshold Low: 1.9 [ppm] Haz-Map
Odor Threshold High: 4.8 [ppm] Haz-Map
[ICSC] Odor threshold from CHEMINFO Haz-Map

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

04 · Handling and storage

Storing and handling 3-Methyl-2-butanone

Storage conditions

Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Store in cool place.

Source: Hazardous Substances Data Bank (HSDB)

Incompatible materials

Vapors may form explosive mixture with air.

Source: Hazardous Substances Data Bank (HSDB)

Reactivity

Ketones, such as 3-METHYLBUTAN-2-ONE, are reactive with many acids and bases liberating heat and flammable gases (e.g., H2). The amount of heat may be sufficient to start a fire in the unreacted portion of the ketone. Ketones react with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable gas (H2) and heat. Ketones are incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides. They react violently with aldehydes, HNO3, HNO3 + H2O2, and HClO4.

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check 3-Methyl-2-butanone in the storage compatibility matrix →

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