Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

2-isopropoxyethanol

2-isopropoxyethanol is a colorless liquid with a mild ethereal odor.

CAS 109-59-1 C5H12O2 104.15 g/mol Warning

01 · Identification

What 2-isopropoxyethanol is

2-isopropoxyethanol is a colorless liquid with a mild ethereal odor. Its molecular formula is C5H12O2 and its molecular weight is 104.15 g/mol. It boils at 144 °C, melts at -60 °C.

Under the GHS it carries the signal word Warning. It is classed as flammable agents - 2nd degree.

CAS number109-59-1
EC number203-685-6
Index number603-013-00-5
Molecular formulaC5H12O2
Molecular weight104.15 g/mol
Chemical class Flammable agents - 2nd degree

Other names for 2-isopropoxyethanol

  • ethylene glycol monoisopropyl ether

02 · GHS classification

Hazards and label elements

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Signal wordWarning
Hazard statements assigned to 2-isopropoxyethanol
CodeHazard statement
H332 Harmful if inhaled.
H312 Harmful in contact with skin.
H319 Causes serious eye irritation.

Precautionary statements: P260, P264, P271, P280, P302, P304, P305, P312, P313, P337, P338, P352

03 · Physical and chemical properties

2-isopropoxyethanol properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Property Value Conditions Source
Boiling point 144 °C (291.2 °F) at 743 mmHg HSDB
139.44 °C (283 °F) NIOSH
141 °C (285.8 °F) at 760 mmHg CAMEO
Melting point -60 °C (-76 °F) ICSC
Density 0.9 g/cm³ NIOSH
0.91 g/cm³ CAMEO
0.903 g/cm³ at 20 °C HSDB
Solubility SOL IN ALL PROP IN WATER, ALC, ETHER; SOL IN ACETONE HSDB
Miscible NIOSH
Miscible (NIOSH, 2024) CAMEO
Vapor pressure 3 mmHg NIOSH
5.2 mmHg at 25 °C HSDB
Flash point 33.33 °C (92 °F) HSDB
33 °C (91.4 °F) CAMEO
Autoignition temperature 240 °C (464 °F) ICSC
Lower explosive limit (LEL) 1.6 % by volume ICSC
Class IC Flammable Liquid: Fl.P. at or above 73 °F and below 100 °F. NIOSH
Upper explosive limit (UEL) 13 % by volume ICSC
Vapor density 3.6 (air = 1) HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

04 · Handling and storage

Storing and handling 2-isopropoxyethanol

Storage conditions

SEE ETHERS. ETHERS SHOULD NOT BE STORED NEAR POWERFUL OXIDIZERS OR IN AREAS OF HIGH FIRE HAZARD. THEY SHOULD BE KEPT COOL AND THE CONTAINERS ELECTRICALLY GROUNDED TO AVOID SPARKS. /ETHERS/

Source: Hazardous Substances Data Bank (HSDB)

Incompatible materials

Oxidizers.

Source: Hazardous Substances Data Bank (HSDB)

Reactivity

ETHYLENE GLYCOL ISOPROPYL ETHER acts both as an alcohol and ether. May react violently with strong oxidizing agents. May generate flammable and/or toxic gases with alkali metals, nitrides, and other strong reducing agents. May initiate the polymerization of isocyanates and epoxides.

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check 2-isopropoxyethanol in the storage compatibility matrix →

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