Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

2,2'-thiodiethanol

2,2'-thiodiethanol is a liquid with a characteristic odor.

CAS 111-48-8 Warning

01 · Identification

What 2,2'-thiodiethanol is

2,2'-thiodiethanol is a liquid with a characteristic odor. It boils at 282 °C, melts at -10.2 °C.

Under the GHS it carries the signal word Warning.

CAS number111-48-8
EC number203-874-3
Index number603-081-00-6

Other names for 2,2'-thiodiethanol

  • thiodiglycol

02 · GHS classification

Hazards and label elements

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Signal wordWarning
Hazard statements assigned to 2,2'-thiodiethanol
CodeHazard statement
H319 Causes serious eye irritation.

Precautionary statements: P264, P280, P305, P313, P337, P338

03 · Physical and chemical properties

2,2'-thiodiethanol properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Property Value Conditions Source
Boiling point 282 °C (539.6 °F) HSDB
282 °C (539.6 °F) at 760 mmHg HMDB
Melting point -10.2 °C (13.6 °F) HSDB
-16 °C (3.2 °F) DOE PAC
-14 °C (6.8 °F) range, midpoint shown ICSC
Density 1.1803 g/cm³ HSDB
1.18 g/cm³ ICSC
1.1793 g/cm³ at 25 °C HSDB
Solubility Miscible with water HSDB
Miscible with ethanol, chloroform, ethyl acetate; soluble in ether; slightly soluble in benzene HSDB
In water, miscible at 20 °C at 20 °C HSDB
Vapor pressure 0.000509 mmHg at 25 °C HSDB
0.0032 mmHg at 25 °C ICSC
0.0032 mmHg Haz-Map
Flash point 113 °C (235.4 °F) HSDB
160 °C (320 °F) Closed cup HSDB
160 °C (320 °F) ICSC
Autoignition temperature 297.78 °C (568 °F) HSDB
260 °C (500 °F) ICSC
Lower explosive limit (LEL) 1.2 % by volume ICSC
Upper explosive limit (UEL) 5.2 % by volume ICSC
Vapor density 4.21 (air = 1) HSDB
4.22 (air = 1) ICSC

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

04 · Handling and storage

Storing and handling 2,2'-thiodiethanol

Storage conditions

Keep container tightly closed in a dry and well-ventilated place.

Source: Hazardous Substances Data Bank (HSDB)

Incompatible materials

Reacts violently with strong acids and strong oxidants. This produces hydrogen sulfide.

Source: Hazardous Substances Data Bank (HSDB)

Planning storage for a mix of chemicals? Check 2,2'-thiodiethanol in the storage compatibility matrix →

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