Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

1,3-Dioxolane

1,3-Dioxolane is a water-white liquid.

CAS 646-06-0 C3H6O2 74.08 g/mol Danger

01 · Identification

What 1,3-Dioxolane is

1,3-Dioxolane is a water-white liquid. Its molecular formula is C3H6O2 and its molecular weight is 74.08 g/mol. It boils at 78 °C, melts at -95 °C, is soluble in water.

Under the GHS it carries the signal word Danger. It is classed as flammable agents - 3rd degree.

CAS number646-06-0
EC number211-463-5
Index number605-017-00-2
Molecular formulaC3H6O2
Molecular weight74.08 g/mol
Chemical class Flammable agents - 3rd degree

02 · GHS classification

Hazards and label elements

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Signal wordDanger
Hazard statements assigned to 1,3-Dioxolane
CodeHazard statement
H225 Highly flammable liquid and vapour.

Precautionary statements: P210, P233, P241, P242, P403

03 · Physical and chemical properties

1,3-Dioxolane properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Property Value Conditions Source
Boiling point 78 °C (172.4 °F) HSDB
78 °C (172.4 °F) at 760 mmHg DOE PAC
Melting point -95 °C (-139 °F) HSDB
-97.2 °C (-143 °F) DOE PAC
Density 1.06 g/cm³ at 20 °C HSDB
8.2 g/cm³ at 20 °C HSDB
1.066 g/cm³ at 20 °C DOE PAC
Solubility Soluble in ethanol, ether, acetone HSDB
Miscible in water HSDB
Vapor pressure 79 mmHg at 20 °C HSDB
79 mmHg Haz-Map
Flash point 1.67 °C (35 °F) HSDB
Vapor density 2.6 (air = 1) HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

04 · Handling and storage

Storing and handling 1,3-Dioxolane

Incompatible materials

Potentially expolsive reaction with lithium perchlorate.

Source: Hazardous Substances Data Bank (HSDB)

Reactivity

Ethers, such as DIOXOLANE, can act as bases. They form salts with strong acids and addition complexes with Lewis acids. The complex between diethyl ether and boron trifluoride is an example. Ethers may react violently with strong oxidizing agents. In other reactions, which typically involve the breaking of the carbon-oxygen bond, ethers are relatively inert.

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check 1,3-Dioxolane in the storage compatibility matrix →

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