Substance profile
1,2,4-Trichlorobenzene
1,2,4-Trichlorobenzene is a colorless liquid with an aromatic odor.
01 · Identification
What 1,2,4-Trichlorobenzene is
1,2,4-Trichlorobenzene is a colorless liquid with an aromatic odor. Its molecular formula is C6H3Cl3 and its molecular weight is 181.4 g/mol. It boils at 214 °C, melts at 16.9 °C.
Under the GHS it carries the signal word Warning. It is classed as hazardous Air Pollutants (HAPs).
02 · GHS classification
Hazards and label elements
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
| Code | Hazard statement |
|---|---|
| H302 | Harmful if swallowed. |
| H315 | Causes skin irritation. |
| H400 | Very toxic to aquatic life. |
| H410 | Very toxic to aquatic life with long lasting effects. |
Precautionary statements: P264, P270, P273, P280, P301, P302, P312, P313, P330, P332, P352, P391, P501
03 · Physical and chemical properties
1,2,4-Trichlorobenzene properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 213.5 °C (416.3 °F) | HSDB | |
| 213.33 °C (416 °F) | NIOSH | ||
| 212.78 °C (415 °F) | at 760 mmHg | CAMEO | |
| Melting point | 16.92 °C (62.5 °F) | HSDB | |
| 17.22 °C (63 °F) | NIOSH | ||
| Density | 1.4483 g/cm³ | HSDB | |
| 0.447 g/cm³ | HSDB | ||
| 1.459 g/cm³ | at 20 °C | HSDB | |
| Solubility | Sparingly soluble in alcohol. Miscible with ether, benzene, petroleum ether, carbon disulfide | HSDB | |
| 0.003% | NIOSH | ||
| In water, 49.0 mg/L at 25 °C | at 25 °C | HSDB | |
| Vapor pressure | 1 mmHg | NIOSH | |
| 0.46 mmHg | at 25 °C | HSDB | |
| 0.3 mmHg | at 25 °C | ICSC | |
| Flash point | 105 °C (221 °F) | HSDB | |
| 105.56 °C (222 °F) | NIOSH | ||
| 110 °C (230 °F) | CAMEO | ||
| Autoignition temperature | 571 °C (1059.8 °F) | HSDB | |
| 571.11 °C (1060 °F) | CAMEO | ||
| Lower explosive limit (LEL) | 2.5 % by volume | DOE PAC | |
| 2.5 % by volume | at 150 °C | HSDB | |
| Upper explosive limit (UEL) | 6.6 % by volume | at 150 °C | HSDB |
| Vapor density | 6.26 (air = 1) | HSDB | |
| Odor threshold | Industrial data report an odor threshold of approx 3 ppm ... | HSDB | |
| Low odor threshold= 24.0 mg/cu m; High odor threshold= 24.0 mg/cu m; Irritating concn= 40.0 mg/cu m | HSDB | ||
| Odor Threshold Low: 2.96 [ppm] | Haz-Map | ||
| Critical temperature and pressure | 453.3 °C (847.9 °F) | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
04 · Handling and storage
Storing and handling 1,2,4-Trichlorobenzene
Storage conditions
1,2,4-Trichlorobenzenes are liquids at room temperature and are shipped in bulk in aluminum tank trucks and steel or stainless steel tank cars.
Source: Hazardous Substances Data Bank (HSDB)
Incompatible materials
... On contact with acids or acid fumes they evolve highly toxic /hydrogen chloride/ fumes. /chlorides/
Source: Hazardous Substances Data Bank (HSDB)
Reactivity
1,2,4-TRICHLOROBENZENE can react vigorously with oxidizing materials (NTP, 1992). Yields hydrogen chloride and phosgene when heated to decomposition (USCG, 1999).
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check 1,2,4-Trichlorobenzene in the storage compatibility matrix →