Safety data sheet reference · CAS 67-66-3

Chloroform SDS

also: chloroform MSDS · safety data sheet · CHCl3 · CAS 67-66-3 · EC 200-663-8 · trichloromethane

Danger Carc. 2 · Category 3 · Acute Tox. 4 · +3 UN 1888 · ADR 6.1 · PG III

Skull and Crossbones GHS06 Health Hazard GHS08

Official PDF from supplier

Sigma-Aldrich ↗ Fisher Scientific ↗ Carl Roth ↗

This page is a reference, not the legal document.

CAS number

67-66-3

EC number

200-663-8

CLP Annex VI index

602-006-00-4

Molecular formula

CHCl3

Molar mass

119.37 g/mol

§ 02 · Hazards identification

Harmonised EU classification

CLP Annex VI · Index 602-006-00-4. A supplier SDS may add self-classified hazards — this is the legal minimum.

H302 Harmful if swallowed. Acute toxicity, oral — Category 4 (Acute Tox. 4)

H315 Causes skin irritation. Skin irritation — Category 2 (Skin Irrit. 2)

H319 Causes serious eye irritation. Eye irritation — Category 2 (Eye Irrit. 2)

H331 Toxic if inhaled. Acute toxicity, inhalation — Category 3

H351 Suspected of causing cancer. Carcinogenicity — Category 2 (Carc. 2)

H372 Causes damage to organs through prolonged or repeated exposure. STOT repeated exposure — Category 1 (STOT RE 1)

Precautionary statements

P201 Obtain special instructions before use.

P260 Do not breathe dust/fume/gas/mist/vapours/spray.

P264 Wash hands thoroughly after handling.

P270 Do not eat, drink or smoke when using this product.

P271 Use only outdoors or in a well-ventilated area.

P280 Wear protective gloves/protective clothing/eye protection/face protection.

P301 IF SWALLOWED: call a POISON CENTER or doctor if you feel unwell.

P302 IF ON SKIN: wash with plenty of water.

P304 IF INHALED: remove person to fresh air and keep comfortable for breathing.

P305 IF IN EYES: rinse cautiously with water for several minutes.

P308 IF exposed or concerned: get medical advice/attention.

P310 Immediately call a POISON CENTER or doctor.

P312 Call a POISON CENTER or doctor if you feel unwell.

P313 Get medical advice/attention.

P314 Get medical advice/attention if you feel unwell.

P330 Rinse mouth.

P332 If skin irritation occurs: get medical advice/attention.

P337 If eye irritation persists: get medical advice/attention.

P338 Remove contact lenses, if present and easy to do. Continue rinsing.

P352 Wash with plenty of water.

§ 07 · Handling and storage

Computed storage verdict

Keep separate from 11 storage groups Acute toxics

Derived from CLP Annex VI classification and CAMEO reactive-group data — not copied from a PDF.

↔ Keep separate

Bases Flammable liquids Flammable solids Compressed gases Mineral acids Organic acids Organic peroxides & self-reactives Oxidizing acids Oxidizers Reactive metals Water-reactives

Full interactive verdict — reactions, gas release on contact, ADR forms →

§ 09 · Physical and chemical properties

Measured properties

Melting point -63.5 °C

Boiling point 61.7 °C

Relative density (water = 1) 1.4832

Source: CAMEO Chemicals (NOAA, public domain); per-value source references stored in the database.

§ 10 · Stability and reactivity

Reactive group (CAMEO/NOAA): Halogenated Organic Compounds. Our database documents 17 incompatible and 13 caution reaction-partner groups for chloroform — including which combinations release gas on contact. See the per-partner breakdown with gas release →

Incompatible

Caution

§ 13 · Disposal considerations

Dispose of waste and residues in accordance with local and national regulations — in the EU under the Waste Framework Directive 2008/98/EC. Never discharge to drains or municipal waste; hand contaminated packaging and unused product to an authorised waste-disposal company. The supplier's SDS section 13 lists the applicable waste codes for the specific product.

§ 14 · Transport information

Road transport — ADR 2025

UN number

UN 1888

Proper shipping name

CHLOROFORM

Class · PG

6.1 · III

Classification code

Transport category

ADR labels

6.1

Hazard ID (Kemler) / UN plate

60

1888

Top: hazard identification number (Kemler). Bottom: UN number — as carried on the orange plate of the transport unit.

Source: UN ADR 2025 (ECE/TRANS/352), Table A. Road (ADR) only — for sea (IMDG) and air (IATA), consult the supplier's SDS §14.

MSDS vs SDS

MSDS vs SDS: is there a difference?

MSDS (Material Safety Data Sheet) is the older name for the same document. In the US, OSHA's Hazard Communication Standard (2012) adopted the GHS-standardised 16-section Safety Data Sheet; in the EU the format is set by REACH Annex II. So a "chloroform MSDS" and a "chloroform SDS" refer to the same document — today it is issued as an SDS. Full breakdown of the differences →

Other acute toxics in our database

Compliance hub

From classification to SDS

The classification above corresponds to Section 2 of a Safety Data Sheet. Learn how a compliant 16-section SDS is structured and authored →

GHS label maker

Build the label for chloroform

Pictograms, signal word and H-statements combined into a compliant label layout →

§ 16 · Sources

Classification: Regulation (EC) No 1272/2008 (CLP), Annex VI
Transport: UN ADR 2025 (UNECE), Table A
Reactivity: NOAA CAMEO Chemicals reactive-group matrix (public domain)
Physical properties: CAMEO Chemicals (NOAA, public domain) — per-value source references stored in the database
Substance data: PubChem · ECHA

Reference aid only. This page summarises the harmonised EU classification and computed storage guidance — it is not a Safety Data Sheet and does not replace one. Always verify hazards, handling and storage against the supplier's SDS (sections 7 and 10) and local regulations before use. Page updated 2026-07-27.

Frequently asked questions

Is an MSDS the same as an SDS?

In practice, yes. MSDS (Material Safety Data Sheet) is the older name for the same document. In the US, OSHA's Hazard Communication Standard (2012) adopted the GHS-standardised 16-section Safety Data Sheet; in the EU the SDS format is set by REACH Annex II. A document you find labelled "chloroform MSDS" is today issued as an SDS.

What GHS pictograms does chloroform require?

Under the harmonised EU classification (CLP Annex VI), chloroform carries GHS06 and GHS08 with the signal word "Danger". Hazard statements: H351, H361d, H331, H302, H372, H315, H319. A supplier's SDS may add self-classified hazards on top of this harmonised minimum.

Where can I download an official chloroform SDS PDF?

From your own supplier — an SDS is issued per product and supplier, so the correct PDF for an inspection is the one matching the product you actually purchased. The supplier links on this page lead to the official SDS libraries of major distributors.