Safety data sheet reference · CAS 75-05-8
Acetonitrile SDS
also: acetonitrile MSDS · safety data sheet · CH3CN · CAS 75-05-8 · EC 200-835-2 · ACN · methyl cyanide
Official PDF from supplier
This page is a reference, not the legal document.
CAS number
75-05-8
EC number
200-835-2
CLP Annex VI index
608-001-00-3
Molecular formula
C2H3N
Molar mass
41.05 g/mol
§ 02 · Hazards identification
Harmonised EU classification
CLP Annex VI · Index 608-001-00-3. A supplier SDS may add self-classified hazards — this is the legal minimum.
Precautionary statements
§ 07 · Handling and storage
Computed storage verdict
Derived from CLP Annex VI classification and CAMEO reactive-group data — not copied from a PDF.
⚠ Highly Flammable
⛔ Never store with
↔ Keep separate
Full interactive verdict — reactions, gas release on contact, ADR forms →
§ 09 · Physical and chemical properties
Measured properties
Fire-relevant values first — flash point and explosion limits decide the storage and ventilation regime.
Flash point
5.6 °C
Explosion limits
4.4 – 16 %
LEL / UEL in air, vol.
Autoignition
523.9 °C
Source: CAMEO Chemicals (NOAA, public domain); per-value source references stored in the database.
§ 10 · Stability and reactivity
Reactive group (CAMEO/NOAA): Nitriles. Our database documents 13 incompatible and 15 caution reaction-partner groups for acetonitrile — including which combinations release gas on contact. See the per-partner breakdown with gas release →
13
Incompatible
15
Caution
§ 13 · Disposal considerations
Dispose of waste and residues in accordance with local and national regulations — in the EU under the Waste Framework Directive 2008/98/EC. Never discharge to drains or municipal waste; hand contaminated packaging and unused product to an authorised waste-disposal company. The supplier's SDS section 13 lists the applicable waste codes for the specific product.
§ 14 · Transport information
Road transport — ADR 2025
UN number
UN 1648
Proper shipping name
ACETONITRILE
Class · PG
3 · II
Classification code
F1
Transport category
2
ADR labels
3
Hazard ID (Kemler) / UN plate
Top: hazard identification number (Kemler). Bottom: UN number — as carried on the orange plate of the transport unit.
Source: UN ADR 2025 (ECE/TRANS/352), Table A. Road (ADR) only — for sea (IMDG) and air (IATA), consult the supplier's SDS §14.
MSDS vs SDS
MSDS vs SDS: is there a difference?
MSDS (Material Safety Data Sheet) is the older name for the same document. In the US, OSHA's Hazard Communication Standard (2012) adopted the GHS-standardised 16-section Safety Data Sheet; in the EU the format is set by REACH Annex II. So a "acetonitrile MSDS" and a "acetonitrile SDS" refer to the same document — today it is issued as an SDS. Full breakdown of the differences →
Other flammable liquids in our database
- (2-butyl-5-nitrobenzofuran-3-yl)[4-(3-dibutylaminopropoxy)phenyl]methanone 141645-23-0
- (R)-p-mentha-1,8-diene;d-limonene 5989-27-5
- (S)-methyl-2-chloropropionate 73246-45-4
- 1-bromo-2-methylpropyl propionate 158894-67-8
- 1-bromo-3,4,5-trifluorobenzene 138526-69-9
- 1-bromo-3,5-difluorobenzene 461-96-1
- 1-bromopropane; n-propyl bromide 106-94-5
- 1-chloro-2,3-epoxypropane; epichlorhydrin 106-89-8
Compliance hub
From classification to SDS
The classification above corresponds to Section 2 of a Safety Data Sheet. Learn how a compliant 16-section SDS is structured and authored →
GHS label maker
Build the label for acetonitrile
Pictograms, signal word and H-statements combined into a compliant label layout →
§ 16 · Sources
- Classification: Regulation (EC) No 1272/2008 (CLP), Annex VI
- Transport: UN ADR 2025 (UNECE), Table A
- Reactivity: NOAA CAMEO Chemicals reactive-group matrix (public domain)
- Physical properties: CAMEO Chemicals (NOAA, public domain) — per-value source references stored in the database
- Substance data: PubChem · ECHA
Reference aid only. This page summarises the harmonised EU classification and computed storage guidance — it is not a Safety Data Sheet and does not replace one. Always verify hazards, handling and storage against the supplier's SDS (sections 7 and 10) and local regulations before use. Page updated 2026-07-27.
Frequently asked questions
Is an MSDS the same as an SDS?
In practice, yes. MSDS (Material Safety Data Sheet) is the older name for the same document. In the US, OSHA's Hazard Communication Standard (2012) adopted the GHS-standardised 16-section Safety Data Sheet; in the EU the SDS format is set by REACH Annex II. A document you find labelled "acetonitrile MSDS" is today issued as an SDS.
What GHS pictograms does acetonitrile require?
Under the harmonised EU classification (CLP Annex VI), acetonitrile carries GHS02 and GHS07 with the signal word "Danger". Hazard statements: H225, H332, H312, H302, H319. A supplier's SDS may add self-classified hazards on top of this harmonised minimum.
What should acetonitrile never be stored with?
Based on its storage class (Flammable liquids), acetonitrile must not share storage with: Organic peroxides & self-reactives; Oxidizing acids; Oxidizers. Verify against the supplier's SDS sections 7 and 10 before finalising storage.
Where can I download an official acetonitrile SDS PDF?
From your own supplier — an SDS is issued per product and supplier, so the correct PDF for an inspection is the one matching the product you actually purchased. The supplier links on this page lead to the official SDS libraries of major distributors.